106787-38-6

Basic information

• Product Name: [(Diethoxy-phosphorylamino)-p-tolyl-methyl]-phosphonic acid diphenyl ester
• CAS NO: 106787-38-6
• Molecular Weight: 489.445
• Mol File: 106787-38-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [(Diethoxy-phosphorylamino)-p-tolyl-methyl]-phosphonic acid diphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(Diethoxy-phosphorylamino)-p-tolyl-methyl]-phosphonic acid diphenyl ester(106787-38-6)
• EPA Substance Registry System: [(Diethoxy-phosphorylamino)-p-tolyl-methyl]-phosphonic acid diphenyl ester(106787-38-6)

Safety Data

• Hazardous Substances Data: 106787-38-6(Hazardous Substances Data)

Upstream product

• 1068-21-9 Diethyl phosphoramidate 
• 4712-55-4 diphenyl hydrogen phosphite 
• 104-87-0 4-methyl-benzaldehyde 
• 5382-00-3 Diphenyl phosphorochloridite 

Relevant articles and documents

Studies on organophosphorus compounds XLVII: Acetyl chloride - A versatile reagent for the synthesis of 1-aminoalkyl- and amino(aryl)methylphosphonic acid derivatives

Acetyl chloride is used successfully in the synthesis of 1-aminoalkyl- and amino(aryl)methylphosphonic acid derivatives by a three-component condensation reaction involving diethyl phosphoramidate, aldehydes and diphenyl phosphite. Furthermore, in the reaction of benzyl carbamate, aldehydes and phosphorus(III) chloride, acetyl chloride facilates the formation of alkyl hydrogen 1-(benzyloxycahronylamino)alkylphosphonates or aryl(benzyloxycarbonylamino)methylphosphonates, key intermediates in the synthesis of phosphonopeptide with a P-N bond. In comparison with other methods, the present variation affords wider scope of application including the use of some aliphatic aldehydes, fair yields and mild reaction conditions.