1067903-47-2Relevant academic research and scientific papers
Entry into a new class of protein kinase inhibitors by pseudo ring design
Furet, Pascal,Caravatti, Giorgio,Guagnano, Vito,Lang, Marc,Meyer, Thomas,Schoepfer, Joseph
, p. 897 - 900 (2008)
A pyrimidin-4-yl-urea motif forming a pseudo ring by intramolecular hydrogen bonding has been designed to mimic the pyrido[2,3-d]pyrimidin-7-one core structure of a well-established class of protein kinase inhibitors. Potent inhibition of a number of prot
