106792-40-9Relevant articles and documents
A strategy to avoid anomalous O-alkylation of 4-hydroxyindole by diethyl bromomalonate
Papageorgiou, George,Corrie, John E. T.
, p. 1101 - 1104 (2005)
Alkylation of 4-hydroxyindole with diethyl bromomalonate under standard conditions (potassium carbonate-acetone) gave the expected indolyloxymalonate ester 3 together with the anomalous indolyloxy-2-bromomalonate 4, Depending on conditions, the ratio of t
JAK INHIBITOR
-
Page/Page column 88, (2009/10/21)
A JAK inhibitor comprising, as an active ingredient, a nitrogen-containing heterocyclic compound represented by formula (I) {wherein W represents a nitrogen atom or -CH-; X represents -C (=O) - or -CHR4- (wherein R4 represents a hydrogen atom, or the like); R1 represents the formula described below [wherein Q1 represents-CR8-(wherein R8 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like); Q2 represents -NR15- (wherein R15 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like); and R5 and R6 may be the same or different and each represents a hydrogen atom, halogen, carboxy, substituted or unsubstituted lower alkyl, or the like], or the like; and R2 and R3 may be the same or different and each represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, or the like} or a pharmaceutically acceptable salt thereof.
Anionically substituted 7-Nitroindoline derivatives and their uses
-
Page/Page column 8; 12, (2010/11/25)
Anionically substituted 7-nitroindoline derivatives are disclosed and their uses as caged compounds from which effector species such as neurotransmitters and amino acids are releasable on irradiation with light.
