1068142-16-4

Upstream product

• 83345-46-4 N-(tert-butyloxycarbonyl)-L-tyrosinol 
• 228570-07-8 toluene-4-sulfonic acid 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 5034-68-4 4-[(2S)-2-amino-3-hydroxypropyl]phenol 

Downstream Products

• 1068142-17-5 (S)-3-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecoxy)phenyl]-2-(methanesulfonylamino)propyl methanesulfonate 
• 1363786-72-4 C₂₅H₂₅F₁₇N₄O₃ 
• 1363786-74-6 C₂₀H₁₇F₁₇N₄O 
• 1363786-76-8 C₂₁H₁₆F₂₀N₄O₃S 
• 1363786-78-0 C₂₁H₁₈F₂₀N₂O₃S 
• 1363786-69-9 C₂₆H₂₈F₁₇NO₆S 
• 1068142-18-6 (S)-N-{1-azido-3-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyloxy)phenyl]prop-2-yl} methanesulfonamide 
• 1068142-14-2 (S)-N-{3-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecoxy)phenyl]-2-(methanesulfonylamino)propyl}-4-toluenesulfonamide 

Relevant academic research and scientific papers

Chiral recyclable fluorous disulfonamide ligand for catalytic enantioselective cyclopropanation of allylic alcohols

Allylic alcohols reacted with Et2Zn and CH2I2 in the presence of a catalytic amount of fluorous disulfonamide 3a to afford the corresponding cyclopropylmethanols in 69%-quantitative yields with 49-85% ee. Recovery of the fluorous ligand 3a was readily performed from the reaction mixture by the fluorous solid-phase extraction (FSPE), and the recovered 3a could be reused without a significant loss of the catalytic activity and enantioselectivity.

Catalytic enantioselective cyclopropanation of allylic alcohols using recyclable fluorous disulfonamide ligand

Cyclopropanation of allylic alcohols with Et2Zn and CH2I2 in the presence of a catalytic amount of fluorous disulfonamide 3 afforded the corresponding cyclopropylmethanols in 69-96% yield with 49-83% ee. The fluorous ligand 3 was readily recovered from the reaction mixture by the fluorous solid-phase extraction (FSPE) and could be reused without a significant loss of the catalytic activity and enantioselectivity.