106836-92-4

Upstream product

• 288-88-0 1,2,4-Triazole 
• 6956-56-5 2,2-dimethoxy-1-phenylethanone 
• 82969-91-3 N,N'-di(1H-1,2,4-triazol-1-yl)sulfoxide 
• 97904-56-8 α-ethoxy-α-hydroxy-acetophenone 

Downstream Products

• 106836-99-1 (1R,2R/1S,2S)-1-Methoxy-2-phenyl-1-(1H-1,2,4-triazol-1-yl)-2-propanol 

Relevant academic research and scientific papers

Synthesis and oral anti-fungal activity of novel 1,3-bis-(azolyl)-2-arylpropan-2-ols

Synthesis of 1-alkoxy- or 1-alkylthio-1,3-bis(azolyl)-2-anylpropan-2-ols is described.The title compounds were examined for their anti-fungal activities in vitro by evaluation of broth dilution MIC values against 3 species of fungi and the inhibitory effe

Chelation-Controlled Grignard Reactions of &α-(1H-1,2,4-Triazol-1-yl) Ketones

The high diastereoselectivity of the Grignard addition to α-(1H-1,2,4-triazol-1-yl) ketones (1,4), α-alkoxy-α-(1H-1,2,4-triazol-1-yl) ketones (7,13) and corresponding imidazolyl derivatives can be rationalized via postulated intermediate chelate complexes 3,9.In this case, alkoxy groups as well as azole substituents may function as ligands.For 2d and 8d an X-ray structural analysis was performed.