1068435-04-0

Basic information

• Product Name: O₆-benzyl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine
• Synonyms: O₆-benzyl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine
• CAS NO: 1068435-04-0
• Molecular Weight: 691.034
• Mol File: 1068435-04-0.mol

Chemical Properties

• CAS DataBase Reference: O₆-benzyl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine(CAS DataBase Reference)
• NIST Chemistry Reference: O₆-benzyl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine(1068435-04-0)
• EPA Substance Registry System: O₆-benzyl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine(1068435-04-0)

Safety Data

• Hazardous Substances Data: 1068435-04-0(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 479408-22-5 O⁶-benzyl-8-bromo-3',5'-O-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 

Downstream Products

• 1124321-44-3 C₂₉H₄₈N₆O₄Si₂ 
• 1124321-44-3 8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 

Relevant articles and documents

Synthesis of DNA-oligonucleotides damaged by arylamine-modified 2′-deoxyguanosine

C8-Arylamine-dG adducts bearing a labile N-formamidine group at the exocyclic amino function were converted into their corresponding 5′-O-DMTr-3′-O-phosphoramidite-C8-arylamine-dG derivatives. These compounds were used for the automated synthesis of site-

Synthesis of DNA strands site-specifically damaged by C8-arylamine purine adducts and effects on various DNA polymerases

C8-Arylamine-dG and C8-arylamine-dA adducts have been prepared using palladium cross-coupling chemistry. These adducts were subsequently converted into the corresponding 5′-O-DMTr-C8-arylamine-3′-O-phosphoramidites and then used for the automated synthesi