1068660-03-6

Basic information

• Product Name: 3-(4-methoxybenzyl)-7-(difluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine
• Synonyms: 3-(4-methoxybenzyl)-7-(difluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine
• CAS NO: 1068660-03-6
• Molecular Weight: 303.311
• Mol File: 1068660-03-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxybenzyl)-7-(difluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxybenzyl)-7-(difluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine(1068660-03-6)
• EPA Substance Registry System: 3-(4-methoxybenzyl)-7-(difluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine(1068660-03-6)

Safety Data

• Hazardous Substances Data: 1068660-03-6(Hazardous Substances Data)

Upstream product

• 41739-23-5 1,1-difluoro-1-phenyl-1,3-butanedione 
• 1285456-65-6 7-[chloro(difluoro)methyl]-3-(4-methoxybenzyl)-5-methyl-3H-imidazo[4,5-b]pyridine 
• 2375-76-0 1-chloro-1,1-difluoropentane-2,4-dione 
• 2393-23-9 4-methoxy-benzylamine 

Relevant articles and documents

A general strategy for the synthesis of difluoromethyl-containing pyrazoles, pyridines and pyrimidines

Difluoromethyl-containing heteroannulated pyridines, pyrimidines and pyrazoles are prepared by a two step method. The regioselective cyclizations of electron-excessive aminoheterocycles, hydrazines and amidines with CF 2Cl-substituted 1,3-dicarbonyl compounds provide the corresponding CF2Cl-substituted heterocycles. Subsequent radical reactions with trimethylstannane or allyltrimethylstannane gave difluoromethyl-containing heteroannulated pyridines, pyrimidines and pyrazoles, respectively.