2375-76-0

Usage

Uses

Used in Specialty Polymers Industry:
1-CHLORO-1,1-DIFLUORO-2,4-PENTANEDIONE is used as a building block for the synthesis of specialty polymers, which have unique properties and applications in various industries, such as automotive, aerospace, and electronics.
Used in Pharmaceuticals Industry:
DFPD is used as a precursor in the production of pharmaceuticals, contributing to the development of new drugs with improved therapeutic properties and reduced side effects.
Used in Agricultural Chemicals Industry:
1-CHLORO-1,1-DIFLUORO-2,4-PENTANEDIONE is utilized in the synthesis of agricultural chemicals, such as pesticides and herbicides, to enhance crop protection and increase agricultural productivity.
Used in Refrigerants Production:
DFPD is used in the production of refrigerants, which are essential for cooling systems in various applications, including residential, commercial, and industrial settings.
Used in Solvents Industry:
1-CHLORO-1,1-DIFLUORO-2,4-PENTANEDIONE serves as a precursor for the development of solvents, which are widely used in various industrial processes, such as cleaning, degreasing, and dissolving substances.
Used in Surfactants Production:
DFPD is used in the synthesis of surfactants, which are crucial in the formulation of detergents, soaps, and other cleaning products, enhancing their effectiveness in removing dirt and stains.
However, it is important to note that 1-CHLORO-1,1-DIFLUORO-2,4-PENTANEDIONE is considered a hazardous chemical and should be handled with care due to its potential health and environmental risks. Proper safety measures and precautions must be taken during its production, storage, and use to minimize any adverse effects.

InChI:InChI=1/C5H5ClF2O2/c1-3(9)2-4(10)5(6,7)8/h2H2,1H3

Upstream product

• 1514-87-0 metyhyl chlorodifluoroacetate 
• 67-64-1 acetone 

Downstream Products

• 164342-39-6 1-choro-1,1-difluoro-3-ethoxymethylene-2,4-pentanedione 
• 1285456-65-6 7-[chloro(difluoro)methyl]-3-(4-methoxybenzyl)-5-methyl-3H-imidazo[4,5-b]pyridine 
• 1316284-16-8 1-tert-butyl-4-(chlorodifluoromethyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 
• 1316284-35-1 3-(4-chlorobenzyl)-7-(chlorodifluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine 
• 1316284-23-7 1-(4-methoxybenzyl)-4-(chlorodifluoromethyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 
• 832746-57-3 4-(chlorodifluoromethyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 1316284-33-9 5-(chlorodifluoromethyl)-1,3,7-trimethylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 1068660-03-6 3-(4-methoxybenzyl)-7-(difluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine 
• 1178533-20-4 7-(difluoromethyl)-1,5-dimethyl-3-phenyl-1,3-dihydro-2H-imidazo[4,5-b]pyridine-2-thione 
• 746607-87-4 4-(difluoromethyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 1316284-41-9 1-cyclohexyl-4-(difluoromethyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 
• 1316284-43-1 1-(4-methoxybenzyl)-4-(difluoromethyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 
• 1316284-51-1 3-(4-chlorobenzyl)-7-(difluoromethyl)-5-methyl-3H-imidazo[4,5-b]pyridine 
• 1316284-53-3 4-(1,1-difluorobut-3-enyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine 

Relevant academic research and scientific papers

A general strategy for the synthesis of difluoromethyl-containing pyrazoles, pyridines and pyrimidines

Difluoromethyl-containing heteroannulated pyridines, pyrimidines and pyrazoles are prepared by a two step method. The regioselective cyclizations of electron-excessive aminoheterocycles, hydrazines and amidines with CF 2Cl-substituted 1,3-dicarbonyl compounds provide the corresponding CF2Cl-substituted heterocycles. Subsequent radical reactions with trimethylstannane or allyltrimethylstannane gave difluoromethyl-containing heteroannulated pyridines, pyrimidines and pyrazoles, respectively.