1068660-66-1Relevant articles and documents
CuI/L-proline-catalyzed synthesis of vinyl sulfides in 95% alcohol
Guo, Sheng-Rong,Yuan, Yan-Qin
experimental part, p. 2722 - 2730 (2009/04/04)
A method for the synthesis of vinyl sulfides using the simple CuI/L-proline as a catalyst system is reported. The best yields were obtained in the 95% ethanol with 10 mol% CuI, 20 mol% L-proline, and 1.2 equiv of K2CO3. The amino acids act as base and excellent promoter for the copper-catalyzed coupling reactions, and this protocol tolerates both aromatic and heterocyclic thiols and avoids using other expensive additives. Copyright ? Taylor & Francis Group, LLC.