106872-30-4Relevant articles and documents
Base assisted substitution of α-amidoalkyl sulfones by nitromethane anion. A new entry to functionalized α-amino acids
Ballini, Roberto,Petrini, Marino
, p. 4449 - 4452 (2007/10/03)
The nitromethane anion reacts with α-amidoalkyl sulfones in THF affording the corresponding nitro derivatives that upon oxidation with alkaline potassium permanganate give the corresponding N-protected α-amino acids.
REACTIONS OF AN ELECTROPHILIC GLYCINE CATION EQUIVALENT WITH GRIGNARD REAGENTS A SIMPLE SYNTHESIS OF β,γ-UNSATURATED AMINO ACIDS
Castelhano, Arlindo L.,Horne, Stephen,Billedeau, Roland,Krantz, Allen
, p. 2435 - 2438 (2007/10/02)
A simple and general synthesis of α-amino acids employing vinyl and alkyl Grignard reagents with a glycine cation equivalent is described.