106877-54-7Relevant articles and documents
REACTION OF BIS-α-DIKETONES WITH UREA IN AN ALKALINE MEDIUM
Savchenko, T. I.,Yatsimirskii, A. K.
, p. 1117 - 1122 (2007/10/02)
The condensation of bis-α-diketones C6H5COCOArCOCOC6H5 and urea with the formation of new hydantoins was investigated in an alkaline medium.The dependence of the reactivity of the bis-α-diketones on the central aryl fragment is described satisfactorily on the basis of a Hammett correlation.It was established that 1,4-di(phenyloxalyl)benzene has high sensitivity to nucleophilic attack, due to the mutal effect of the α-dicarbonyl reaction centers.From analysis of the 13C NMR and UV spectra it follows that the reactivity is probably determined not by the difference in the electron distribution at the carbons of the carbonyl groups but by their steric orientation.