3363-97-1

Basic information

• Product Name: 1-[4-(2-Oxo-2-phenylacetyl)phenyl]-2-phenylethane-1,2-dione
• Synonyms: 1,4-BISBENZIL;1,4-BIS(BENZOYLCARBONYL)BENZENE;1,4-BIS(PHENYLGLYOXALOYL)BENZENE;1,1'-(p-Phenylene)bis(2-phenylethanedione);1,4-bis(phenylglyoxyloyl)benzene;2,2’-diphenyl-1,1’-(1,4-phenylene)diethanedione;bisbenzil;ethanedione],1,1’-(1,4-phenylene)bis[2-phenyl-
• CAS NO: 3363-97-1
• Molecular Formula: C₂₂H₁₄O₄
• Molecular Weight: 342.34
• Mol File: 3363-97-1.mol
• Article Data: 24

Chemical Properties

• Melting Point: 125°C
• Boiling Point: 549 °C at 760 mmHg
• Flash Point: 237.7 °C
• Appearance: /
• Density: 1.261 g/cm³
• Vapor Pressure: 4.22E-12mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 1-[4-(2-Oxo-2-phenylacetyl)phenyl]-2-phenylethane-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(2-Oxo-2-phenylacetyl)phenyl]-2-phenylethane-1,2-dione(3363-97-1)
• EPA Substance Registry System: 1-[4-(2-Oxo-2-phenylacetyl)phenyl]-2-phenylethane-1,2-dione(3363-97-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3363-97-1(Hazardous Substances Data)

Usage

General Description

1-[4-(2-Oxo-2-phenylacetyl)phenyl]-2-phenylethane-1,2-dione is a complex synthetic organic compound that belongs to the family of benzophenones, characterized by its structures containing three phenyl rings along with two carbonyl groups, and a side chain containing another carbonyl group. As its name suggests, it consists of a phenylacetic acid (or 2-oxo-2-phenylacetyl) chain substituted at the fourth position of one of the phenyl rings. Its chemical properties will depend largely on these functional groups. Its specific applications are not well documented in the literature, but like other benzophenones, it may potentially be used in pharmaceuticals or organic materials.

InChI:InChI=1/C22H14O4/c23-19(15-7-3-1-4-8-15)21(25)17-11-13-18(14-12-17)22(26)20(24)16-9-5-2-6-10-16/h1-14H

Upstream product

• 1009-61-6 1,4-Diacetylbenzene 
• 100-52-7 benzaldehyde 
• 935-14-8 1,4-diethynylbenzene 
• 17763-67-6 Phenyl triflate 
• 591-50-4 iodobenzene 
• 536-74-3 phenylacetylene 
• 97245-29-9 2,3-dioxosuccindialdehyde 
• 3363-92-6 1,4-bis (phenylacetyl)benzene 
• 7789-45-9 copper(II)bromide 
• 6921-34-2 benzylmagnesium chloride 
• 623-26-7 terephthalonitrile 
• 624-38-4 para-diiodobenzene 
• 1608-41-9 1,4-distyrylbenzene 
• 1849-27-0 1,4-bis(2-phenylethynyl)benzene 

Downstream Products

• 3432-73-3 3,3'-(1,4-phenylene)bis(2,4,5-triphenylcyclopenta-2,4-dien-1-one) 
• 59443-08-2 1,4-Bis-(α-hydroxyphenacetyl)-benzol 
• 64946-05-0 2,2'-diphenyl-3,3'-p-phenylene-bis-quinoxalin-6-ylamine 
• 1259293-91-8 1,4-bis(2-phenyl-1,1,2,2-tetrafluoroethyl)benzene 
• 41758-31-0 3,3'-diphenyl-2,2'-p-phenylene-bis-quinoxaline 
• 121400-84-8 1,4-bis(5-phenyl-2,4,6,8-tetraaza-3,7-dioxobicyclo<3.3.0>octan-1-yl)benzene 
• 86386-79-0 C₄₆H₃₂N₆O₂ 
• 121400-87-1 1-phenyl-5-<4-(2-phenyl-1,2-dioxoethyl)phenyl>-2,4,6,8-tetraazabicyclo<3.3.0>octane-3,7-dione 
• 106877-54-7 1,4-di(4-phenyl-4-hydantoinyl)benzene 
• 106877-59-2 1-(4-phenyl-4-hydantoinyl)-4-(phenyloxalyl)benzene 

Relevant articles and documents

One-pot cascade synthesis of α-diketones from aldehydes and ketones in water by using a bifunctional iron nanocomposite catalyst

A new methodology for the synthesis of α-diketones was reportedviaa one-pot cascade process from aldehydes and ketones catalyzed by a bifunctional iron nanocomposite using H2O2as a green oxidant in water. The one-pot strategy showed excellent catalytic stability, comprehensive suitability of substrates and important practical utility for directly synthesizing biologically active and medicinally valuable N-heterocyclesviaan intermittent process.

A Bifunctional Iron Nanocomposite Catalyst for Efficient Oxidation of Alkenes to Ketones and 1,2-Diketones

We herein report the fabrication of a bifunctional iron nanocomposite catalyst, in which two catalytically active sites of Fe-Nx and Fe phosphate, as oxidation and Lewis acid sites, were simultaneously integrated into a hierarchical N,P-dual doped porous carbon. As a bifunctional catalyst, it exhibited high efficiency for direct oxidative cleavage of alkenes into ketones or their oxidation into 1,2-diketones with a broad substrate scope and high functional group tolerance using TBHP as the oxidant in water under mild reaction conditions. Furthermore, it could be easily recovered for successive recycling without appreciable loss of activity. Mechanistic studies disclose that the direct oxidation of alkenes proceeds via the formation of an epoxide as intermediate followed by either acid-catalyzed Meinwald rearrangement to give ketones with one carbon shorter or nucleophilic ring-opening to generate 1,2-diketones in a cascade manner. This study not only opens up a fancy pathway in the rational design of Fe-N-C catalysts but also offers a simple and efficient method for accessing industrially important ketones and 1,2-diketones from alkenes in a cost-effective and environmentally benign fashion.

Electrochemical synthesis of 1,2-diketones from alkynes under transition-metal-catalyst-free conditions

We report an electrochemical protocol for the direct oxidation of internal alkynes in air to provide 1,2-diketones. A variety of functional groups and heterocycle-containing substrates can be tolerated well under mild conditions.