106894-91-1Relevant academic research and scientific papers
Condensed pyrroles: N1-benzyl-2,5,6-trimethylpyrrolo[2,3-d]- 1,3-oxazin-4-ones and n1-benzyl-2,5,6-trimethyl-3-substituted-pyrrolo[2,3-d] pyrimidin-4-ones
Hassan,Bayomi,Ali
, p. 764 - 768 (2007/10/03)
Convenient routes are reported for the synthesis of fused pyrrolo[2, 3-d]-1, 3-oxazine 2 and pyrrolo[2, 3-d]pyrimidine derivatives 4 from N-benzyl-2-amino-3-t-butoxycarbonyl-4, 5-dimethylpyrrole 1.
Synthesis of 2,7-disubstituted-5,6-dimethylpyrrolo-[2,3-d]-1,3-oxazin-4- ones as antifungal agents
Player,Sowell Sr.
, p. 209 - 214 (2007/10/02)
A series of novel 5,6-dimethylpyrrolo[2,3-d]-1,3-oxazin-4-ones were synthesized from 2-amino-3-tert-butoxy-carbonyl-4,5-dimethylpyrroles. Two methods were used, cyclodehydration of 2-acylamino-3-carboxypyrroles with acetic anhydride and direct conversion of the 5,6-dimethylpyrrolo[2,3-d]- 1,3-oxazin-2,4-diones to the title compounds with an anhydride directly providing the 2 substituent. Molecular modeling techniques revealed that these pyrrolo[2,3-d]oxazinones were rigid analogues of the allylamine antifungals. The compounds were tested for in vitro activity against Tricophyton and Scopulariopsis sp.
SYNTHESIS OF 3,7-DIHYDRO-4H-PYRROLOPYRIMIDIN-4-ONES
Jorgensen, Anker
, p. 997 - 1006 (2007/10/02)
A series of 9 new 3-aryl-3,7-dihydro-2,5,6-trimethyl-7-phenylmethyl-4H-pyrrolopyrimidin-4-ones 2a-i were prepared in 44-46percent yields by heating methyl 2-acetamido-4,5-dimethyl-1-phenylmethyl-1H-pyrrolo-3-carboxylate 1 in a mixture of phosphorus
