1069-82-5 Usage
2,3-Dimyristoyl-sn-glycerol
A synthetic lipid molecule that belongs to the category of glycerophospholipids.
Glycerophospholipids
A class of lipids that contain a glycerol backbone and two fatty acid chains, with one of the fatty acids being phosphorylated.
Myristoyl groups
Saturated fatty acid chains with a 14-carbon length, attached to the sn-1 and sn-2 positions of the glycerol backbone.
Lipid bilayers
A structural component of cell membranes, formed by the arrangement of lipid molecules in two parallel layers, with the hydrophobic tails facing each other and the hydrophilic heads facing the aqueous environment.
Liposomal drug delivery systems
A method of encapsulating drugs within small, spherical vesicles made of lipid bilayers, to improve drug stability, solubility, and targeted delivery.
Cell membrane structure
The physical arrangement and organization of lipids, proteins, and other molecules that form the outer layer of a cell, maintaining its shape and separating its internal environment from the external surroundings.
Membrane functions
The various roles played by cell membranes, such as regulating the transport of molecules, facilitating cell signaling, and providing mechanical support.
Biochemical and biophysical studies
Research areas focused on understanding the chemical and physical properties of biological molecules and processes, including lipid-protein interactions and membrane dynamics.
Check Digit Verification of cas no
The CAS Registry Mumber 1069-82-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,6 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1069-82:
(6*1)+(5*0)+(4*6)+(3*9)+(2*8)+(1*2)=75
75 % 10 = 5
So 1069-82-5 is a valid CAS Registry Number.
1069-82-5Relevant academic research and scientific papers
The Chiral Target of Daptomycin Is the 2R,2′S Stereoisomer of Phosphatidylglycerol
Moreira, Ryan,Taylor, Scott D.
, (2021/12/09)
Daptomycin (dap) is an important antibiotic that interacts with the bacterial membrane lipid phosphatidylglycerol (PG) in a calcium-dependent manner. The enantiomer of dap (ent-dap) was synthesized and was found to be 85-fold less active than dap against
Synthesis of boron cluster lipids: Closo-dodecaborate as an alternative hydrophilic function of boronated liposomes for neutron capture therapy
Lee, Jong-Dae,Ueno, Manabu,Miyajima, Yusuke,Nakamura, Hiroyuki
, p. 323 - 326 (2008/02/03)
(Chemical Equation Presented) We succeeded in the synthesis of the double-tailed boron cluster lipids 4a-c and 5a-c, which have a B 12H11S moiety as a hydrophilic function, by S-alkylation of B12H11SH (BSH) with bromoacetyl and chloroacetocarbamate derivatives of diacylglycerols for a liposomal boron delivery system on neutron capture therapy. Calcein encapsulation experiments revealed that the liposomes, prepared from the boron cluster lipid 4b, DMPC, PEG-DSPE, and cholesterol, are stable at 37°C in FBS solution for 24 h.
