106910-85-4

Basic information

• Product Name: ethyl (3R)-4-benzylMorpholine-3-carboxylate
• Synonyms: ethyl (3R)-4-benzylMorpholine-3-carboxylate;(3R)-4-(phenylmethyl)-3-Morpholinecarboxylic acid ethyl ester;(R)-Ethyl 4-benzylmorpholine-3-carboxylate
• CAS NO: 106910-85-4
• Molecular Formula: C₁₄H₁₉NO₃
• Molecular Weight: 249.30556
• Mol File: 106910-85-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 330.328°C at 760 mmHg
• Flash Point: 153.577°C
• Appearance: /
• Density: 1.128g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.531
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ethyl (3R)-4-benzylMorpholine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (3R)-4-benzylMorpholine-3-carboxylate(106910-85-4)
• EPA Substance Registry System: ethyl (3R)-4-benzylMorpholine-3-carboxylate(106910-85-4)

Safety Data

• Hazardous Substances Data: 106910-85-4(Hazardous Substances Data)

Usage

General Description

Ethyl (3R)-4-benzylmorpholine-3-carboxylate is a chemical compound that belongs to the class of morpholine derivatives. It is an ester, specifically the ethyl ester, of (3R)-4-benzylmorpholine-3-carboxylic acid. ethyl (3R)-4-benzylMorpholine-3-carboxylate has potential applications in medicinal chemistry and drug development due to its pharmacological properties. It may have activities as an anticonvulsant, anxiolytic, or antidepressant agent. Its structure and functional groups make it a promising candidate for further research and development in the pharmaceutical industry.

InChI:InChI=1/C14H19NO3/c1-2-18-14(16)13-11-17-9-8-15(13)10-12-6-4-3-5-7-12/h3-7,13H,2,8-11H2,1H3/t13-/m1/s1

Upstream product

• 106973-36-8 (3R)-5-oxo-4-(phenylmethyl)-3-morpholinecarboxylic acid 
• 106910-77-4 N-(phenylmethyl)-D-serine 
• 100-52-7 benzaldehyde 
• 106973-39-1 ethyl (R)-4-benzyl-5-oxomorpholine-3-carboxylate 

Downstream Products

• 929047-50-7 (3R)-4-(phenylmethyl)-3-morpholinecarboxylic acid 

Relevant articles and documents

PYRIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS

There are provided according to the invention novel compounds of formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: X represents a nitrogen atom; Y represents -C(H2)-, (-C(H2)-)2, -S(O2)- or -C(=O)-; Z represents -C(H2)-, -S(O2)-, -N(Rz)-, or an oxygen or sulphur atom; A represents hydrogen or -CH2OH; Rz represents hydrogen, C1-6 alkyl, C1-6 alkoxy, -COR7 or -SO2R7; R1 represents halogen, C1-6 alkyl, C1-6 alkoxy, =O, haloC1-6 alkyl, haloC1-6 alkoxy, hydroxyl or -CH2OH; m represents an integer from 0 to 3; R2 represents halogen, =O, C1-6alkyl (optionally substituted by one or more hydroxyl groups), -COOR7, -CONR7R8, C1-6 alkoxy, haloC1-6 alkyl, haloC1-6alkoxy or C1-6 alkyloC1-6 alkyl; n represents an integer from 0 to 3; p and q independently represent an integer from 0 to 2; R3 represents an -aryl, -heteroaryl, -heterocyclyl, -aryl-aryl, -aryl-heteroaryl, -aryl-heterocyclyl, -heteroaryl-aryl, -heteroaryl-heteroaryl, -heteroaryl-heterocyclyl, -heterocyclyl-aryl, -heterocyclyl-heteroaryl or -heterocyclyl-heterocyclyl group, all of which may be optionally substituted by one or more (e.g. 1, 2 or 3) halogen, C1-6 alkyl (optionally substituted by one or more hydroxyl groups), C3-8cycloalkyl, C1-6 alkoxy, hydroxyl, haloC1-6alkyl, haloC1-6 alkoxy, cyano, -S-C1-6 alkyl, -SO-C1-6 alkyl, -SO2-C1-6 alkyl, -COR7, -CONR7R8, -NR7R8, -NR7COC1-6 alkyl, -NR7SO2-C1-6alkyl, C1-6 alkyl-NR7R8, -OCONR7R8 , -NR7CO2R8 or -SO2NR7R8 groups; R4 and R5 independently represent C1-6 alkyl, or R4 and R5 together with the carbon atom to which they are attached may together form a C3-8cycloalkyl group; R6 represents halogen, C1-6 alkyl, C3-8cycloalkyl, C1-6 alkoxy, haloC1-6 alkyl or haloC1-6 alkoxy; s represents an integer from 0 to 4; R7 and R8 independently represent hydrogen, C1-6 alkyl or C3-8cycloalkyl; or solvates thereof.