106910-93-4Relevant academic research and scientific papers
Four-component quinazoline synthesis from simple anilines, aromatic aldehydes and ammonium iodide under metal-free conditions
Chen, Jinjin,Chang, Dan,Xiao, Fuhong,Deng, Guo-Jun
, p. 5459 - 5463 (2018)
A four-component procedure for the preparation of substituted quinazolines from anilines, aromatic aldehydes and ammonium iodide is described. The C-H bond ortho to the amino group in anilines was directly functionalized under metal-free conditions. Two a
Ru(II)-Catalyzed C-H Activation and Annulation Reaction via Carbon-Carbon Triple Bond Cleavage
Prakash, Rashmi,Bora, Bidisha R.,Boruah, Romesh C.,Gogoi, Sanjib
, p. 2297 - 2300 (2018/04/30)
An unprecedented Ru(II)-catalyzed C-H activation and annulation reaction, which proceeds via C-C triple bond cleavage, is reported. This reaction of 2-phenyldihydrophthalazinediones with alkynes, which works most efficiently in the presence of bidented ligand 1,3-bis(diphenylphosphino)propane, affords good yields of substituted quinazolines.
Rearrangement Reactions of 1,3,6-Triaryl-1,4-dihydro-s-tetrazines leading to 2,4-Diarylquinazolines, 1-Anilino-3,5-diaryl-1H-1,2,4-triazoles, 1,3,5-Triaryl-1H-1,2,4-triazoles, and 2,5-Diaryl-1H-1,3,4-oxadiazoles. X-ray Structure Determination of 6-Isopropyl-2,4-diphenylquinazoline
Hunter, Daniel,Neilson, Douglas G.,Weakley, Timothy J.R.
, p. 2709 - 2712 (2007/10/02)
1,3,6-Triaryl-1,4-dihydro-s-tetrazines (2c-g) rearrange on heating at ca. 200 deg C to 2,4-diarylquinazolines (for which an X-ray determination was carried out on the 6-isopropyl compound) and 1-anilino-3,5-diaryl-1H-1,2,4-triazoles as major products.Hydrolysis in chloroform solution of the title compounds (2) and their 1-alkyl analogues gives rise to 1-aryl (or alkyl)-3,5-diaryl-1H-1,2,4-triazoles and 2,5-diaryl-1,3,4-oxadiazoles.
