106911-02-8Relevant academic research and scientific papers
Copper-catalyzed aerobic carboxygenation and N-arylation of [1,2,3]triazolo[1,5-a]pyridines towards pyridinium triazolinone ylides
Pankajakshan, Sreekumar,Chng, Zhi Guang,Ganguly, Rakesh,Loh, Teck Peng
, p. 5929 - 5931 (2015)
Copper-catalyzed aerobic oxyarylation of [1,2,3]triazolo[1,5-a]pyridines is developed. Notably molecular oxygen was utilized as one of the reagents and the transformation resulted in the formation of novel pyridinium triazolinone ylides. A basic mechanism for the one-pot process is proposed and further functionalization of the ylidic products were also presented.
Ni-catalyzed alkenylation of triazolopyridines: Synthesis of 2,6-disubstituted pyridines
Liu, Sheng,Sawicki, James,Driver, Tom G.
, p. 3744 - 3747 (2012/08/28)
A synthetic strategy to access 2,6-disubstituted pyridines from triazolopyridines through a regioselective nickel-catalyzed alkenylation reaction of the C7-H bond is described. The N2 fragment embedded in the resulting C-H functionalized triazolopyridine can be readily excised using acidic or oxidative conditions to unmask the pyridine.
Triazolopyridines. Part 6. Ring Opening Reactions of Triazolopyridines
Jones, Gurnos,Mouat, Deborah J.,Tonkinson, Daryl J.
, p. 2719 - 2724 (2007/10/02)
The triazole ring in 1,2,3-triazolo-pyridines and -quinolines, and in 1,2,3-triazoloisoquinolines can be opened with loss of nitrogen.The reagents described are bromine, aqueous sulphuric acid, glacial acetic acid, and selenium dioxide; the products from the triazolopyridines are dibromomethyl, hydroxymethyl, acetoxymethyl, and acyl derivatives of pyridine.The generality of the reactions is discussed.The first reported reaction in which the six-membered ring of a 1,2,3-triazolopyridine is opened, by hydride reduction, gives a triazolylbutadiene.
