106913-68-2Relevant academic research and scientific papers
REACTION OF α-DIKETONES WITH ETHANOLAMINE
Alcaide, Benito,Perez-Ossorio, Rafael,Plumet, Joaquin,Rico, Manuel,Rodriguez-Campos, Ignacio M.
, p. 1381 - 1384 (1986)
Butanedione and ethanolamine react to yield 4,8-diaza-1,5-dioxadecalin 3, 2,3-epoxy-8-aza-1,4,5-trioxadecalin 4, and 2-hydroxy-1,6-dihydro-oxazine 5a according to the molar ratios of the reagents.With benzil and 1-phenyl-1,2-propanedione only the related oxazines 5 are obtained in equilibrium with their open-chain tautomers.
Reaction of α-Diketones with 2-Amino Alcohols. Intramolecular Competitive 6-exo-trig vs 5-endo-trig Processes. A Systematic and Kinetic Study
Alcaide, Benito,Plumet, Joaquin,Rodriguez-Campos, Ignacio M.
, p. 2446 - 2454 (2007/10/02)
2-Aminoethanol and C-substituted derivatives 1 react with diacetyl, benzil, and 1-phenyl-1,2-propanedione, models of α-diketones 2 to give with remarkable regio- and stereoselectivity 2-hydroxy-5,6-dihydro-2H-1,4-oxazines 3, cis-octahydrooxazino3,2-
