
Tetrahedron Letters p. 1381 - 1384 (1986)
Update date:2022-07-29
Topics: Regioselectivity applications Reaction Overview Catalysts and Conditions
Alcaide, Benito
Perez-Ossorio, Rafael
Plumet, Joaquin
Rico, Manuel
Rodriguez-Campos, Ignacio M.
Butanedione and ethanolamine react to yield 4,8-diaza-1,5-dioxadecalin 3, 2,3-epoxy-8-aza-1,4,5-trioxadecalin 4, and 2-hydroxy-1,6-dihydro-oxazine 5a according to the molar ratios of the reagents.With benzil and 1-phenyl-1,2-propanedione only the related oxazines 5 are obtained in equilibrium with their open-chain tautomers.
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