106928-30-7 Usage
Preparation
To a cooled ( 20 C°) solution of the formamide (6.5 mg) in pyridine (0.4 mL) under Ar atmosphere was added phosphoryl chloride (11 mL) and the mixture was stirred at the same temperature for 40 min. Addition of saturated aq. NaHCO3, extraction with 10% MeOH/ CH2Cl2, standard work-up, and PTLC (hexane/EtOAc, 4:1) afforded (±)-hapalindole U 1629 (4.5 mg, 73%) as colorless needles; mp 240–242 C° (CH2Cl2/hexane). During the synthesis and evaluation of a series of arachidonate epoxy inhibitors, 1631 was prepared in 85% yield by dehydration of the formamide 1630 with phosphoryl chloride.
Check Digit Verification of cas no
The CAS Registry Mumber 106928-30-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,9,2 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 106928-30:
(8*1)+(7*0)+(6*6)+(5*9)+(4*2)+(3*8)+(2*3)+(1*0)=127
127 % 10 = 7
So 106928-30-7 is a valid CAS Registry Number.
106928-30-7Relevant articles and documents
Stereodivergent Total Synthesis of Hapalindoles, Fischerindoles, Hapalonamide H, and Ambiguine H Alkaloids by Developing a Biomimetic, Redox-Neutral, Cascade Prins-Type Cyclization
Sahu, Samrat,Das, Beauty,Maji, Modhu Sudan
, p. 6485 - 6489 (2018/10/24)
A stereoselective, redox-neutral, Br?nsted acid-catalyzed cascade Prins-type cyclization between indole and aldehyde is described to access several structurally diverse indole terpenoid scaffolds in a single step. Applying this concept, stereodivergent to
Total synthesis of hapalindoles J and U
Rafferty, Ryan J.,Williams, Robert M.
, p. 519 - 524 (2012/03/26)
The total synthesis of d,l-hapalindoles J and U has been accomplished. Hapalindole J was prepared in 11% overall yield over 11 synthetic steps and hapalindole U was prepared in 25% overall yield over 13 synthetic steps from commercially available materials. The route employs a novel silyl ether-based strategy for accessing the 6:5:6:6 ring system of the hapalindoles rapidly and in good yields.
