131572-81-1

Basic information

• Product Name: rac-(R)-6,6,9-trimethyl-2-tosyl-9-vinyl-6,7,8,9-tetrahydronaphtho[1,2,3-cd]indol-10(2H)-one
• CAS NO: 131572-81-1
• Molecular Weight: 445.582
• Mol File: 131572-81-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: rac-(R)-6,6,9-trimethyl-2-tosyl-9-vinyl-6,7,8,9-tetrahydronaphtho[1,2,3-cd]indol-10(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: rac-(R)-6,6,9-trimethyl-2-tosyl-9-vinyl-6,7,8,9-tetrahydronaphtho[1,2,3-cd]indol-10(2H)-one(131572-81-1)
• EPA Substance Registry System: rac-(R)-6,6,9-trimethyl-2-tosyl-9-vinyl-6,7,8,9-tetrahydronaphtho[1,2,3-cd]indol-10(2H)-one(131572-81-1)

Safety Data

• Hazardous Substances Data: 131572-81-1(Hazardous Substances Data)

Upstream product

• 131572-83-3 6,6,9-Trimethyl-9-vinyl-2,7,8,9-tetrahydro-6H-2-aza-aceanthrylen-10-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 1352410-68-4 C₁₅H₃₀O₂Si₂ 
• 1352410-70-8 rac-6-(2-(1-(tert-butyldimethylsilyl)-1H-indol-4-yl)propan-2-yl)-3-methyl-2-((trimethylsilyl)oxy)-3-vinylcyclohexanone 
• 131573-12-1 2,6,7,8,9,10-hexahydro-10ξ-hydroxy-6,6,9-trimethyl-2-p-toluenesulfonyl-9-vinylnaphth<1,2,3-cd>indole 
• 124337-89-9 2,6,7,8,9,10-hexahydro-6,6,9-trimethyl-2-p-toluenesulfonyl-9-vinylnaphth<1.2.3-cd>indole 
• 131572-74-2 2,6,6a,7,8,9-hexahydro-6ξ-hydroxy-6,6,9-trimethyl-2-p-toluenesulfonyl-9-vinylnaphth<1,2,3-cd>indole 

Downstream Products

• 101968-75-6 (+/-)-hapalindole U 

Relevant articles and documents

Total synthesis of hapalindoles J and U

The total synthesis of d,l-hapalindoles J and U has been accomplished. Hapalindole J was prepared in 11% overall yield over 11 synthetic steps and hapalindole U was prepared in 25% overall yield over 13 synthetic steps from commercially available materials. The route employs a novel silyl ether-based strategy for accessing the 6:5:6:6 ring system of the hapalindoles rapidly and in good yields.

SYNTHETIC STUDIES OF MARINE ALKALOIDS HAPALINDOLES. Part 1. TOTAL SYNTHESIS OF (+/-)-HAPALINDOLES J and M

The first concise synthesis of marine indole alkaloids (+/-) hapalindoles J (4) and M (5) was achieved in seven or six steps starting from a readily available compound 6 using important key reactions, 6 -> 7 -> 8 and 35 -> 41 or 5.