106976-50-5Relevant academic research and scientific papers
4-pyridinyl-n-acyl-l-phenylalanines
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, (2008/06/13)
Compounds of Formula I have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4 and are useful for treating disease whose symptoms and or damage are related to the binding of VCAM-1 to cells expressing VLA-4.
N-aroylphenylalanine derivative VCAM-1 inhibitors
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, (2008/06/13)
Compounds of the formula: are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 to cells expr
Thioamide derivatives
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, (2008/06/13)
It has been discovered that compounds of the formula: and the pharmaceutically acceptable salts and esters thereof wherein X and Y are as defined below, inhibit the binding of VCAM-1 to VLA-4 and are useful in treating inflammation associated with chronic inflammatory diseases such as rheumatoid arthritis (RA), multiple sclerosis, (MS), asthma, and inflammatory bowel disease (I BD).
Rotational Barriers of Bis(2,6-disubstituted-aryl) Ketones and Bis(2,6-disubstituted-aryl)methanes and -ethanes and Their Mono- and Bis(tricarbonylchromium) Complexes
Weissensteiner, Walter,Scharf, Josef,Schloegl, Karl
, p. 1210 - 1215 (2007/10/02)
Bis(2,6-dialkylphenyl)methanes and -ethanes and bis(2,6-dialkylphenyl) ketones and their mono- and bis(tricarbonylchromium) complexes have been prepared and their variable-temperature NMR spectra recorded.Monocomplexation increases the isomerization barri
