107044-46-2Relevant academic research and scientific papers
Aromatic Benzylation: Part VI - Some More Experiments on Nuclear Benzylation of 2,4-Dihydroxydesoxybenzoin and Synthesis of C-Benzylated Isoflavones
Jain, A. C.,Nayyar, Naresh K.,Arya, P.
, p. 646 - 648 (2007/10/02)
2,4-Dihydroxydesoxybenzoin (1a) reacts with benzyl bromide in the presence of MeOH-KOH at room temperature to give 4-benzyl ether (1b) (31.4percent yield), 3-C-benzyl derivative (2a, 12.2percent), 5-C-benzyl derivative (3a, 2.8percent), 3,5-di-C-benzyl derivative (4a, 1.4percent) and 3-C-benzyl-4-benzyl ether (2b, 0.7percent).The desoxybenzoins 2a, 3a and 4a have also been converted into the corresponding C-benzylated isoflavones (5a, 5b and 5c).
