1070879-23-0 Usage
Uses
Used in Pharmaceutical Industry:
4-Bromo-6-methylquinoline is used as a synthetic intermediate for the development of biologically active compounds, including potential drug candidates. Its unique structure allows for the creation of a wide range of functionalized quinoline derivatives with potential applications in medicinal chemistry and drug discovery.
Used in Research and Development:
In the field of organic synthesis, 4-Bromo-6-methylquinoline serves as a versatile building block, enabling the exploration and development of new chemical reactions. Its use in research contributes to the advancement of knowledge in organic chemistry and the discovery of novel compounds with potential therapeutic properties.
Used in Medicinal Chemistry:
4-Bromo-6-methylquinoline is utilized as a key component in the preparation of functionalized quinoline derivatives, which are of interest in medicinal chemistry due to their potential applications in the treatment of various diseases and conditions. 4-Bromo-6-methylquinoline's structural features facilitate the design and synthesis of new molecules with improved pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1070879-23-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,0,8,7 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1070879-23:
(9*1)+(8*0)+(7*7)+(6*0)+(5*8)+(4*7)+(3*9)+(2*2)+(1*3)=160
160 % 10 = 0
So 1070879-23-0 is a valid CAS Registry Number.
1070879-23-0Relevant articles and documents
A highly practical and convenient halogenation of fused heterocyclic N-oxides
Wang, Dong,Wang, Yuxi,Zhao, Junjie,Li, Linna,Miao, Longfei,Wang, Dong,Sun, Hua,Yu, Peng
, p. 5762 - 5768 (2016/08/30)
A novel, simple and practical method for the regioselective halogenation of fused heterocyclic N-oxides has been developed. It employs Vilsmeier reagent, generated in situ by POX3and DMF, as both the activating agent and the nucleophilic halide source. The method is amenable across a broad range of substrates, including quinolines, isoquinolines and the diazine N-oxides, possessing a variety of substitution patterns. Furthermore, all of the reagents associated are cheap and easy to obtain. The potential extension of this method to a one-pot oxidation/halogenation sequence that obviates the need for isolation of the N-oxide intermediates is also presented.
Process for piperidine intermediates for quinine, quinidine and analogs thereof
-
, (2008/06/13)
Quinine, quinidine and analogs thereof, are prepared by reacting a 4-quinolyllithium compound with a 4,5-erythro-5-ethyl(or vinyl)-quinuclidine-2ε -carboxaldehyde or the corresponding quinuclidine-2-carboxylic acid alkyl ester. Also described, inter alia, is the preparation of a 4,5-erythro-5-ethyl(or vinyl)-quinuclidine-2ε-carboxaldehyde, and a 4,5-crythro-5-ethyl(or vinyl)-quinuclidine-2ε -carboxylic acid and esters thereof. The end products are useful as antimalarial and antiarrhythmic agents.
