1070879-27-4Relevant articles and documents
Quinoline Derivatives and Their Use as ALK and ALK L1196M Inhibitors
-
Paragraph 0263-0264; 0310-0311, (2019/05/04)
The present invention relates to quinoline derivatives and a use thereof as inhibitors of ALK and mutated ALK. A pharmaceutical composition containing quinoline derivatives of chemical formula 1 or each of pharmaceutically acceptable salt thereof, has an effect of preventing or treating diseases associated with ALK and ALK L1196M, in other words, proliferative diseases caused by abnormal cell growth and function or behavior thereof.COPYRIGHT KIPO 2019
Novel cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
-
Page 105, (2010/02/09)
The present invention relates to a cyclic urea compound of formula I: as defined herein. The invention is also directed to the process for its preparation, pharmaceutical composition comprising it and its pharmaceutical use, as an inhibitor on a protein kinase. Thus, it is useful for preventing or treating a physiological disorder capable of being modulated by inhibiting the activity of a protein kinase, such as a solid tumor.