1070892-66-8 Usage
Uses
Used in Organic Synthesis:
N-(3-Fluoro-2-chloro-phenyl)-forMaMide is utilized as a key intermediate in organic synthesis for the construction of complex organic molecules. Its unique structural features, including the fluoro and chloro substitutions on the phenyl ring, provide versatility in chemical reactions, facilitating the synthesis of a variety of compounds with diverse applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-(3-Fluoro-2-chloro-phenyl)-forMaMide is employed as a building block for the development of new pharmaceuticals. Its structural attributes make it a promising candidate for the design of drugs targeting specific biological pathways or receptors, potentially leading to the creation of novel therapeutic agents for various diseases.
Used as a Reagent in Chemical Reactions:
N-(3-Fluoro-2-chloro-phenyl)-forMaMide also serves as a reagent in various chemical reactions, enabling the modification or synthesis of other compounds. Its reactivity and stability contribute to the efficiency and selectivity of these reactions, making it a valuable component in the synthesis of a wide range of chemical products.
Used as a Research Tool in Structure-Activity Relationship Studies:
In the study of structure-activity relationships of biologically active compounds, N-(3-Fluoro-2-chloro-phenyl)-forMaMide is used as a research tool. Its incorporation into different molecular frameworks allows researchers to probe the effects of structural variations on biological activity, providing insights into the design of more potent and selective drug candidates.
Used in Pharmaceutical Development:
N-(3-Fluoro-2-chloro-phenyl)-forMaMide is applied in the pharmaceutical industry as a precursor for the development of new drugs. Its unique chemical properties and potential for modification make it an attractive starting point for the creation of innovative therapeutic agents aimed at addressing unmet medical needs.
Check Digit Verification of cas no
The CAS Registry Mumber 1070892-66-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,0,8,9 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1070892-66:
(9*1)+(8*0)+(7*7)+(6*0)+(5*8)+(4*9)+(3*2)+(2*6)+(1*6)=158
158 % 10 = 8
So 1070892-66-8 is a valid CAS Registry Number.
1070892-66-8Relevant academic research and scientific papers
NH4I-promoted N-acylation of amines via the transamidation of DMF and DMA under metal-free conditions
Chen, Jiahui,Jia, Jing,Guo, Ziyi,Zhang, Jitan,Xie, Meihua
supporting information, p. 1426 - 1429 (2019/05/06)
An unprecedented NH4I-promoted N-formylation and N-acetylization of various amines with dimethylformamide (DMF)and dimethylacetamide (DMA)has been developed. This protocol shows broad substrate scope for aromatic, aliphatic, and heterocyclic amines, which provides a metal-free strategy for N-acylation featuring mild reaction conditions, as well as inexpensive and readily available starting materials.
GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO
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Page/Page column 102, (2008/12/04)
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
