1070901-45-9Relevant academic research and scientific papers
A tandem one-pot, microwave-assisted synthesis of regiochemically differentiated 1,2,4,5-tetrahydro-1,4-benzodiazepin-3-ones
De Silva, Ravindra A.,Santra, Soumava,Andreana, Peter R.
, p. 4541 - 4544 (2008)
(Chemical Equation Presented) A one-pot, two-step synthesis of the title compounds employs a multicomponent Ugl condensation reaction, microwave irradiation, and Fe(0) as a reductant. Two pathways are accessible; both routes utilize bifunctional, o-nitro-substituted arenes leading to either C2, N4, C5 substitution (A) or C2, N4 substitution (B).
