107096-41-3

Upstream product

• 1003-29-8 2-pyrrole aldehyde 
• 89981-01-1 2-methylmercaptobenzyl bromide 
• 33384-77-9 2-(methylthio)benzyl alcohol 
• 107096-40-2 1-(2-Methylthiobenzyl)pyrrole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 107096-42-4 1-(2-Methylthiobenzyl)pyrrole-2-carboxaldehyde oxime 
• 221318-21-4 1-<2-(methylthio)benzyl>-1H-pyrrole-2-methanol 
• 221318-22-5 1-(2-mercaptobenzyl)-1H-pyrrole-2-methanol 
• 107096-43-5 1-(2-Methylthiobenzyl)pyrrole-2-carbonitrile 
• 107096-45-7 1-(2-Methylthiobenzyl)pyrrole-2-carboxylic acid chloride 
• 107096-44-6 1-(2-Methylthiobenzyl)pyrrole-2-carboxylic acid 
• 107096-48-0 1-(2-Methylthiobenzyl)pyrrole-2-carboxyamide 
• 107096-50-4 1-(2-Ethylthiobenzyl)pyrrole-2-carboxyamide 
• 107096-51-5 1-(2-Ethylthiobenzyl)pyrrole-2-carboxylic acid 
• 107096-46-8 Methyl 1-(2-methylthiobenzyl)pyrrole-2-carboxylate 
• 99141-25-0 1-(2-mercaptobenzyl)pyrrole-2-carboxyamide 

Relevant academic research and scientific papers

Polycondensed heterocycles. X. A new method for the preparation of pyrrolo[2,1-c][1,4]benzothiazepines by intramolecular Mitsunobu cyclisation

A modified Mitsunobu reaction of 2-hydroxymethylpyrrole and suitable thiophenol derivatives lead to intermediates which can be easily elaborated and eventually cyclised to the title compounds. The cyclisation step consists of another Mitsunobu reaction variation by which an 'activated' pyrrole is N- alkylated intramolecularly, under very mild conditions.

Polycondensed Heterocycles. II. A New Preparative Route to 11-Oxo-5H,11H-pyrrolobenzothiazepine.

6-Methylthio-10-oxo-5H,10H-pyrroloisoquinoline 11 was isolated in an attempted synthesis of 11-oxo-5H,11H-pyrrolobenzothiazepine 1 from 1-(2-methylthiobenzyl)pyrrole-2-carboxylic acid chloride 9, obtained using as starting material o-me