107150-69-6

Upstream product

• 554-12-1 propanoic acid methyl ester 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 99865-71-1 α-methyl-(E)-ferulic acid 
• 74-88-4 methyl iodide 
• 2605-68-7 methyl 2-(triphenylphosphoranylidene)propionate 

Downstream Products

• 70570-20-6 (E)-2-methyl-3-(3,4-dimethoxyphenyl)acrylic acid 
• 53979-33-2 3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid 
• 7350-60-9 3-(3,4-dimethoxyphenyl)-2-methylacrylic acid 

Relevant academic research and scientific papers

A facile Zn-mediated stereoselective synthesis of (E)- and (Z)-trisubstituted alkenes from Baylis-Hillman adducts in water and its application

A simple and efficient stereoselective synthesis of (E)- and (Z)-trisubstituted alkenes has been accomplished by treatment of the acetyl derivatives of the Baylis-Hillman adducts with Zn in saturated aq. NH 4C1 solution under reflux. The method has been utilized for the preparation of the two chiral insect pheromones, dominicalure-I and dominicalure-II, of the lesser grain borer Rhyzopertha dominica (F). Copyright

Facile stereoselective synthesis of (E)- and (Z)-α-substituted cinnamates: stereospecific dehydration reaction with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and copper(II) chloride

A highly stereoselective method for the synthesis of (E)- and (Z)-α-substituted cinnamates in good yield has been achieved by?dehydration reaction of anti- and syn-α-substituted-β-hydroxyphenylpropiolate using EDC. This facile method has been used to synt

Very short and efficient syntheses of the spermine alkaloid kukoamine A and analogs using isolable succinimidyl cinnamates

Direct selective acylation of the primary amino functions of spermine and spermidine with a variety of isolable succinimidyl cinnamates, followed by catalytic hydrogenation, gave high yields of the spermine alkaloid kukoamine A and analogs suitable for structure-activity relationship studies. Suitable succinimidyl cinnamates were readily obtained through Wittig reaction of aromatic aldehydes with the ylides Ph3P=CRCO2Me, followed by saponification and activation with N-hydroxysuccinimide in the presence of N,N'-dicyclohexylcarbodiimide. Copyright