1071528-72-7

Basic information

• Product Name: 4-ethyl-N-(4-(7-methoxy-1,5-naphthyridin-4-ylthio)phenyl)-6-p-tolylpyridazin-3-amine
• Synonyms: 4-ethyl-N-(4-(7-methoxy-1,5-naphthyridin-4-ylthio)phenyl)-6-p-tolylpyridazin-3-amine
• CAS NO: 1071528-72-7
• Molecular Weight: 479.605
• Mol File: 1071528-72-7.mol

Chemical Properties

• CAS DataBase Reference: 4-ethyl-N-(4-(7-methoxy-1,5-naphthyridin-4-ylthio)phenyl)-6-p-tolylpyridazin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethyl-N-(4-(7-methoxy-1,5-naphthyridin-4-ylthio)phenyl)-6-p-tolylpyridazin-3-amine(1071528-72-7)
• EPA Substance Registry System: 4-ethyl-N-(4-(7-methoxy-1,5-naphthyridin-4-ylthio)phenyl)-6-p-tolylpyridazin-3-amine(1071528-72-7)

Safety Data

• Hazardous Substances Data: 1071528-72-7(Hazardous Substances Data)

Upstream product

• 1071541-27-9 3-chloro-4-ethyl-6-p-tolylpyridazine 
• 1071539-92-8 4-(7-methoxy-1,5-naphthyridin-4-ylthio)benzenamine 
• 952059-69-7 8-chloro-3-methoxy-1,5-naphthyridine 
• 952059-71-1 7-methoxy-1H-[1,5]naphthyridin-4-one 
• 50720-12-2 3-bromo-5-methoxypyridine 
• 625-92-3 3,5-dibromopyridine 
• 64436-92-6 3-amino-5-methoxypyridine 
• 952059-70-0 5-[(5-methoxy-pyridin-3-ylamino)-methylene]-2,2-dimethyl-[1,3]dioxane-4,6-dione 

Relevant articles and documents

Aurora Kinase Modulators and Method of Use

The present invention relates to chemical compounds having a general formula I wherein A1-8, D′, L1, L2, R1, R6-8 and n are defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of such kinases. For example, the compounds are capable of modulating Aurora kinase thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.

AURORA KINASE MODULATORS AND METHOD OF USE

The present invention relates to chemical compounds having a general formula I {INSERT STRUCTURE HERE} wherein A1-8, D,, L1, L2, R1, R6-8 and n are defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of such kinases. For example, the compounds are capable of modulating Aurora kinase thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.