1071766-85-2

Basic information

• Product Name: 2-(6-chloro-1,1-dioxo-3-[(pyridin-3-ylmethyl)amino]-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinone
• CAS NO: 1071766-85-2
• Molecular Weight: 560.057
• Mol File: 1071766-85-2.mol

Chemical Properties

• CAS DataBase Reference: 2-(6-chloro-1,1-dioxo-3-[(pyridin-3-ylmethyl)amino]-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(6-chloro-1,1-dioxo-3-[(pyridin-3-ylmethyl)amino]-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinone(1071766-85-2)
• EPA Substance Registry System: 2-(6-chloro-1,1-dioxo-3-[(pyridin-3-ylmethyl)amino]-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinone(1071766-85-2)

Safety Data

• Hazardous Substances Data: 1071766-85-2(Hazardous Substances Data)

Upstream product

• 3731-52-0 3-Aminomethylpyridine 
• 1071766-73-8 2-(6-chloro-1,1-dioxo-3-methylthio-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinone 

Relevant articles and documents

Synthesis and cytotoxicity testing of novel 2-(3-substituted-6-chloro-1,1- dioxo-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinones

A new series of thirteen 2-[3-(substituted amino)-6-chloro-1,1-dioxo-1,4,2- benzodithiazin-7-yl]-3-phenyl-4(3H)-quinazolinones 4-16 were prepared in order to evaluate their cytotoxic activity against 12 human cancer cell lines. The bioassay indicated that the quinazolinone derivatives 5, 8-12, 15, and 16 possess cancer-cell growth-inhibitory properties. Compounds 5 and 12 showed a high level of selectivity for certain cell lines. The most active compounds 9, 10, 15, and 16 showed moderate antiproliferative activity and were approximately 4-fold less potent than cisplatin.