107196-00-9Relevant academic research and scientific papers
(Z)-1-Aryl-1-haloalkenes as Intermediates in the Vilsmeier Haloformylation of Aryl Ketones
Lilienkampf, Annamaria,Johansson, Mikael P.,Waehaelae, Kristiina
, p. 3387 - 3390 (2003)
(Equation Presented) Vilsmeier reagents give (Z)-1-aryl-1-haloalkenes from aryl ketones bearing an electron-donating substituent at the ortho- or para-position. These haloalkenes are intermediates in the Vilsmeier haloformylation of the aryl ketones. Anot
Catalyst-free hydrochlorination protocol for terminal arylalkynes with hydrogen chloride
Xu, Cai-Xia,Ma, Cun-Hua,Xiao, Fu-Rong,Chen, Hong-Wei,Dai, Bin
supporting information, p. 1683 - 1685 (2016/11/12)
We present a simple and straightforward protocol for hydrochlorination of terminal arylalkynes to vinyl chlorides using hydrogen chloride under mild reaction conditions. This protocol does not involve any metal catalysts or additives. It is simple, inexpensive, and easy to prepare, and exhibits good reaction activity. The hydrochlorination proceeds smoothly to yield unique regioselective products via the Markovnikov addition rule.
