1072123-34-2Relevant academic research and scientific papers
Advanced palladium free approach to the synthesis of substituted alkene oxindoles: Via aluminum-promoted Knoevenagel reaction
Novikova, Daria S.,Grigoreva, Tatyana A.,Zolotarev, Andrey A.,Garabadzhiu, Alexander V.,Tribulovich, Vyacheslav G.
, p. 34543 - 34551 (2018/10/24)
A synthetic route for the synthesis of C24, as well as for the design of focused libraries of direct AMPK activators was developed based on a convergent strategy. The proposed scheme corresponds to the current trends in C-H bond functionalization. The use of aluminum isopropoxide for the Knoevenagel condensation of oxindole with benzophenones is a noticeable point of this work.
Stereoselective synthesis of 3-alkylideneoxindoles by palladium-catalyzed cyclization reaction of 2-(alkynyl)aryl isocyanates with organoboron reagents
Miura, Tomoya,Toyoshima, Takeharu,Takahashi, Yusuke,Murakami, Masahiro
supporting information; experimental part, p. 4887 - 4889 (2009/05/07)
(Chemical Equation Presented) A palladium(0)/monophosphine catalyst promotes a cyclization reaction of 2-(alkynyl)aryl isocyanates with organoboron reagents to produce stereodefined 3-alkylideneoxindoles. The alkynyl and isocyanato groups undergo oxidativ
