1072227-66-7

Basic information

• Product Name: methyl 2,2-diphenyl-2-((S)-1-tosyl-pyrrolidin-3-yl)-acetate
• Synonyms: methyl 2,2-diphenyl-2-((S)-1-tosyl-pyrrolidin-3-yl)-acetate
• CAS NO: 1072227-66-7
• Molecular Weight: 449.571
• Mol File: 1072227-66-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,2-diphenyl-2-((S)-1-tosyl-pyrrolidin-3-yl)-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,2-diphenyl-2-((S)-1-tosyl-pyrrolidin-3-yl)-acetate(1072227-66-7)
• EPA Substance Registry System: methyl 2,2-diphenyl-2-((S)-1-tosyl-pyrrolidin-3-yl)-acetate(1072227-66-7)

Safety Data

• Hazardous Substances Data: 1072227-66-7(Hazardous Substances Data)

Upstream product

• 3469-00-9 methyl 2,2-diphenylacetate 

Downstream Products

• 133099-07-7 (S)-darifenacin hydrobromide 
• 1072227-73-6 2,2-diphenyl-2-{(S)-1-[2-(2,3-dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-acetic acid methyl ester 
• 586346-94-3 darifenacin hydrochloride 
• 133099-04-4 darifenacin 

Relevant articles and documents

NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS

The present invention relates to novel and improved processes for the preparation of intermediates of darifenacin, darifenacin and its pharmaceutically acceptable salts. Darifenacin is chemically known as 3 -(S)-(-)-(l -carbamoyl- 1,1 -diphenylmethyl)-l- [2- (2,3-dihydro benzofuran-5-yl)ethyl]pyrrolidine and represented by formula-2. The invention also relates to the novel polymorphs of the pharmaceutically acceptable salts of darifenacin and the methods for their re aration.