586346-94-3

Basic information

• Product Name: darifenacin hydrochloride
• Synonyms: darifenacin hydrochloride
• CAS NO: 586346-94-3
• Molecular Weight: 463.019
• Mol File: 586346-94-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: darifenacin hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: darifenacin hydrochloride(586346-94-3)
• EPA Substance Registry System: darifenacin hydrochloride(586346-94-3)

Safety Data

• Hazardous Substances Data: 586346-94-3(Hazardous Substances Data)

Upstream product

• 133099-09-9 (S)-diphenyl-[1-(toluene-4-sulfonyl)-pyrrolidin-3-yl]-acetonitrile 
• 134002-26-9 (S)-2,2-diphenyl-2-(pyrrolidin-3-yl)-acetamide L-tartrate 
• 134002-25-8 2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetamide 
• 133099-11-3 (S)-2,2-diphenyl-2-(pyrrolidin-3-yl)-acetonitrile 
• 127264-14-6 2,3-dihydro-5-(2-bromoethyl)benzofuran 
• 943034-50-2 2-(2,3-dihydrobenzofuran-5-yl)ethylchloride 
• 133099-04-4 darifenacin 
• 64089-34-5 2-chloro-1-(2,3-dihydrobenzofuran-5-yl)ethanone 
• 3469-00-9 methyl 2,2-diphenylacetate 
• 86-29-3 Diphenylacetonitrile 
• 1072227-66-7 methyl 2,2-diphenyl-2-((S)-1-tosyl-pyrrolidin-3-yl)-acetate 
• 1072227-71-4 2,2-diphenyl-2-((S)-pyrrolidin-3-yl)-acetic acid methyl ester 

Relevant articles and documents

NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS

The present invention relates to novel and improved processes for the preparation of intermediates of darifenacin, darifenacin and its pharmaceutically acceptable salts. Darifenacin is chemically known as 3 -(S)-(-)-(l -carbamoyl- 1,1 -diphenylmethyl)-l- [2- (2,3-dihydro benzofuran-5-yl)ethyl]pyrrolidine and represented by formula-2. The invention also relates to the novel polymorphs of the pharmaceutically acceptable salts of darifenacin and the methods for their re aration.