107273-07-4Relevant academic research and scientific papers
Copper-Catalyzed N?F Bond Activation for Uniform Intramolecular C?H Amination Yielding Pyrrolidines and Piperidines
Bafaluy, Daniel,Mu?oz-Molina, José María,Funes-Ardoiz, Ignacio,Herold, Sebastian,de Aguirre, Adiran J.,Zhang, Hongwei,Maseras, Feliu,Belderrain, Tomás R.,Pérez, Pedro J.,Mu?iz, Kilian
supporting information, p. 8912 - 8916 (2019/05/29)
The dual function of the N?F bond as an effective oxidant and subsequent nitrogen source in intramolecular aliphatic C?H functionalization reactions is explored. Copper catalysis is demonstrated to exercise full regio- and chemoselectivity control, which
An Iodine-Catalyzed Hofmann-L?ffler Reaction
Martínez, Claudio,Mu?iz, Kilian
, p. 8287 - 8291 (2015/07/07)
Iodine reagents have been identified as economically and ecologically benign alternatives to transition metals, although their application as molecular catalysts in challenging C-H oxidation reactions has remained elusive. An attractive iodine oxidation catalysis is now shown to promote the convenient conversion of carbon-hydrogen bonds into carbon-nitrogen bonds with unprecedented complete selectivity. The reaction proceeds by two interlocked catalytic cycles comprising a radical chain reaction, which is initiated by visible light as energy source. This unorthodox synthetic strategy for the direct oxidative amination of alkyl groups has no biosynthetic precedence and provides an efficient and straightforward access to a general class of saturated nitrogenated heterocycles.
Ring opening of cyclic N,O-acetals with allyltrimethylsilane under Lewis acidic conditions
Bates, Roderick W.,Lu, Yongna,Cai, Melody Peiling
experimental part, p. 7852 - 7858 (2009/12/26)
Five and six-membered cyclic N,O-acetals with N-carboxyalkyl and sulfonyl groups undergo clean and high yielding ring opening with allyltrimethylsilane in the presence of strong Lewis acids to give homoallylic amine derivatives.
Bioinspired polyene cyclization promoted by intermolecular chiral acetal-SnCl4 or chiral N-acetal-TiCl4: Investigation of the mechanism and identification of the key intermediates
Zhao, Yu-Jun,Loh, Teck-Peng
supporting information; experimental part, p. 10024 - 10029 (2009/02/04)
New strategies using chiral acetal or chiral mixed-acetal in the presence of Lewis acids (SnCl4 or TiCl4) to promote polyene cyclization reaction are described. Acetal-promoted and mixed-acetal-promoted polyene cyclization products a
