1072809-99-4Relevant academic research and scientific papers
Metal-Free Synthesis of 4-Aryl-2-quinolone Derivatives by Iodine-Mediated Intramolecular C?H Amidation
Ghosh, Subhankar,Chattopadhyay, Shital K.
, p. 4727 - 4738 (2019)
A metal-free synthesis of a range of 4-aryl-2-quinolone derivatives has been developed which utilizes an iodine-mediated intramolecular C?H amidation of 3,3-diarylacryl amides as the key step. Electron-withdrawing or -donating substituents in either of th
Pd-Catalyzed α-Selective C-H Functionalization of Olefins: En Route to 4-Imino-β-Lactams
Kong, Wei-Jun,Liu, Yue-Jin,Xu, Hui,Chen, Yan-Qiao,Dai, Hui-Xiong,Yu, Jin-Quan
supporting information, p. 2146 - 2149 (2016/03/05)
Pd-catalyzed α-olefinic C-H activation of simple α,β-unsaturated olefins has been developed. 4-imino-β-lactam derivatives were readily synthesized via activation of α-olefinic C-H bonds with excellent cis stereoselectivity. A wide range of heterocycles at the β-position are compatible with this reaction. The product of 4-imino-β-lactam derivatives can be readily converted to 2-aminoquinoline which exists extensively in pharmaceutical drugs and natural products.
Tandem-type Pd(ii)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence: A novel route to 4-aryl-2-quinolinones
Inamoto, Kiyofumi,Kawasaki, Junpei,Hiroya, Kou,Kondo, Yoshinori,Doi, Takayuki
, p. 4332 - 4334 (2012/05/20)
A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential Pd(ii)-catalyzed reactions - the oxidative Heck reaction and the intramolecular C-H amidation - both of which smoothly proceed in the presence of a single catalytic system in a one-pot manner. The Royal Society of Chemistry 2012.
Palladium-catalyzed intramolecular amidation of C(sp2)-H bonds: Synthesis of 4-aryl-2-quinolinones
Inamoto, Kiyofumi,Saito, Tadataka,Hiroya, Kou,Doi, Takayuki
supporting information; experimental part, p. 3900 - 3903 (2010/07/05)
Figure presented A catalytic synthetic approach for the synthesis of 2-quinolinone compounds through a Pd-catalyzed C(sp2)-H functionalization/intramolecular amidation sequence is described. The cyclization process efficiently proceeds in the p
Synthesis of β-, γ-, and δ-lactams via Pd(II)-catalyzed C-H activation reactions
Wasa, Masayuki,Yu, Jin-Quan
supporting information; experimental part, p. 14058 - 14059 (2009/03/11)
Pd(II)-catalyzed intramolecular amination of sp2 and sp3 C-H bonds are developed using a combination of CuCl2 and AgOAc as the oxidant. The reaction protocol tolerates the presence of a double bond in the substrates. This catalytic reaction provides practical access to a wide range of β-, γ-, and δ-lactams. Copyright
