1072840-99-3 Usage
Uses
Used in Pharmaceutical Industry:
FMOC-Leu-Bt is used as a building block for the synthesis of various peptides and peptidomimetics. Its application in this industry is due to its ability to facilitate the formation of stable carboxylate anions, which aids in the synthesis process.
Used in Research and Development:
FMOC-Leu-Bt is used as a reagent for the preparation of diverse derivatives, including polypeptidal benzotriazolides, aminoxypeptides, depsipeptides, and heterocyclic peptidomimetics. Its application in research and development is attributed to its versatility in creating a wide range of peptide derivatives.
Used in Diagnostics and Imaging:
FMOC-Leu-Bt is used as a component in the synthesis of tagged peptides and peptidomimetics, particularly those with fluorescent labels. Its application in this field is due to its ability to enhance the detection and visualization of peptides in various diagnostic and imaging techniques.
Used in Bioconjugation:
FMOC-Leu-Bt is used as a linker for the formation of N, O, S, and C linked peptide conjugates. Its application in bioconjugation is because of its ability to provide stable and specific linkages between peptides and other biomolecules, which is essential for various biological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1072840-99-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,2,8,4 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1072840-99:
(9*1)+(8*0)+(7*7)+(6*2)+(5*8)+(4*4)+(3*0)+(2*9)+(1*9)=153
153 % 10 = 3
So 1072840-99-3 is a valid CAS Registry Number.
1072840-99-3Relevant academic research and scientific papers
Benzotriazole-assisted solid-phase assembly of Leu-Enkephalin, amyloid β segment 34-42, and other "difficult" peptide sequences
Katritzky, Alan R.,Haase, Danniebelle N.,Johnsons, Jodie V.,Chung, Alfred
body text, p. 2028 - 2032 (2009/08/07)
Microwave-assisted solid-phase syntheses of six "difficult" peptides, H-VVSVV-NH2 (3), H-VVVSVV-NH2(4), H-VIVIG-OH (5), H-TVTVTV-NH2 (6), H-VKDGYI-NH2 (7), and H-VKDVYI-NH2 (8), were achieved utilizing N-(Fmoc-α-aminoacyl) benzotriazoles. Extension to the syntheses of Leu-enkephalin (9) and amyloid-β (34-42) (10) demonstrates that this strategy comprises an efficient route to new and known "difficult" peptides.
Synthesis of N-urethane protected β-amino alcohols employing N-(protected-α-aminoacyl)benzotriazoles
Sureshbabu, Vommina V.,Sudarshan,Muralidhar,Narendra
, p. 683 - 685 (2008/09/20)
A simple and racemisation-free synthesis of N-urethane protected α-amino/peptidyl alcohols by the reduction of the corresponding easily accessible N-acylbenzotriazoles is described. The method is practical, straightforward, fast and efficient for the synt
