1072840-99-3 Usage
Uses
Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:Polypeptidal benzotriazolidesPeptidomimetics, such as aminoxypeptides, depsipeptides and heterocyclic peptidomimeticsTagged peptides and peptidomimetics, particularly those with fluorescent labels,N, O, S, and C linked peptide conjugates
Check Digit Verification of cas no
The CAS Registry Mumber 1072840-99-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,2,8,4 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1072840-99:
(9*1)+(8*0)+(7*7)+(6*2)+(5*8)+(4*4)+(3*0)+(2*9)+(1*9)=153
153 % 10 = 3
So 1072840-99-3 is a valid CAS Registry Number.
1072840-99-3Relevant articles and documents
Benzotriazole-assisted solid-phase assembly of Leu-Enkephalin, amyloid β segment 34-42, and other "difficult" peptide sequences
Katritzky, Alan R.,Haase, Danniebelle N.,Johnsons, Jodie V.,Chung, Alfred
body text, p. 2028 - 2032 (2009/08/07)
Microwave-assisted solid-phase syntheses of six "difficult" peptides, H-VVSVV-NH2 (3), H-VVVSVV-NH2(4), H-VIVIG-OH (5), H-TVTVTV-NH2 (6), H-VKDGYI-NH2 (7), and H-VKDVYI-NH2 (8), were achieved utilizing N-(Fmoc-α-aminoacyl) benzotriazoles. Extension to the syntheses of Leu-enkephalin (9) and amyloid-β (34-42) (10) demonstrates that this strategy comprises an efficient route to new and known "difficult" peptides.
