1072902-88-5

Basic information

• Product Name: N-[(phenylmethoxy)carbonyl]-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
• Synonyms: N-[(phenylmethoxy)carbonyl]-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
• CAS NO: 1072902-88-5
• Molecular Weight: 601.868
• Mol File: 1072902-88-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[(phenylmethoxy)carbonyl]-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(phenylmethoxy)carbonyl]-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester(1072902-88-5)
• EPA Substance Registry System: N-[(phenylmethoxy)carbonyl]-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester(1072902-88-5)

Safety Data

• Hazardous Substances Data: 1072902-88-5(Hazardous Substances Data)

Upstream product

• 73-32-5 L-isoleucine 
• 31139-36-3 dibenzyl dicarbonate 
• 3160-59-6 N-Cbz-L-Isoleucine 
• 104871-99-0 (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one 

Downstream Products

• 1072902-75-0 OMDM-188 

Relevant articles and documents

Assay and inhibition of diacylglycerol lipase activity

A series of N-formyl-α-amino acid esters of β-lactone derivatives structurally related to tetrahydrolipstatin (THL) and O-3841 were synthesized that inhibit human and murine diacylglycerol lipase (DAGL) activities. New ether lipid reporter compounds were developed for an in vitro assay to efficiently screen inhibitors of 1,2-diacyl-sn-glycerol hydrolysis and related lipase activities using fluorescence resonance energy transfer (FRET). A standardized thin layer chromatography (TLC) radioassay of diacylglycerol lipase activity utilizing the labeled endogenous substrate [1″- 14C]1-stearoyl-2-arachidonoyl-sn-glycerol with phosphorimaging detection was used to quantify inhibition by following formation of the initial product [1″-14C]2-arachidonoylglycerol and further hydrolysis under the assay conditions to [1-14C]arachidonic acid.