1072902-89-6Relevant articles and documents
Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leads
West, Nicholas P.,Cergol, Katie M.,Xue, Millie,Randall, Elizabeth J.,Britton, Warwick J.,Payne, Richard J.
supporting information; experimental part, p. 5166 - 5168 (2011/06/10)
The first targeted inhibitors of an essential M. tuberculosis cell wall lipase, Rv3802c, are described. Lead compounds exhibited nanomolar inhibition of the enzyme, and encouraging antibacterial activity against M. tuberculosis in vitro, supporting Rv3802c as a novel TB drug target.