1073-39-8

Basic information

• Product Name: 4-Bromobenzocyclobutene
• Synonyms: 3-BROMO-BICYCLO[4.2.0]OCTA-1,3,5-TRIENE;4-Bromobenzocyclobutene;4-bromocyclobutabenzene;1-broMo-4-(cyclobut-1-en-1-yl)benzene;4-broMobicyclo[4.2.0]octa-1(6),2,4-triene;4-BrBCB 4-Bromobenzocyclobutene;4-Bromo-1,2-dihydrobenzocyclobutene;4-BROMO-BENZOCYCLOBUTANE
• CAS NO: 1073-39-8
• Molecular Formula: C₈H₇Br
• Molecular Weight: 183.05
• Product Categories: Aluminium foil bag/Fluoride bottle or on your request
• Mol File: 1073-39-8.mol

Chemical Properties

• Boiling Point: 221.4 °C at 760 mmHg
• Flash Point: 100℃
• Appearance: /
• Density: 1.470 g/mL at 25 °C
• Vapor Pressure: 0.159mmHg at 25°C
• Refractive Index: n20/D1.589
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Bromobenzocyclobutene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromobenzocyclobutene(1073-39-8)
• EPA Substance Registry System: 4-Bromobenzocyclobutene(1073-39-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-51
• WGK Germany: 3
• Hazardous Substances Data: 1073-39-8(Hazardous Substances Data)

Usage

Chemical Properties

colorless or light yellow liquid

InChI:InChI=1/C8H7Br/c9-8-4-3-6-1-2-7(6)5-8/h3-5H,1-2H2

Upstream product

• 694-87-1 benzocyclobutene 
• 4181-31-1 4-Brom-1,2-dijod-benzocyclobuten 
• 4235-46-5 4,α,α,α',α'-pentabromo-o-xylene 
• 552-45-4 1-chloromethyl-2-methylbenzene 

Downstream Products

• 875-94-5 4-carboxybenzocyclobutene 
• 112892-88-3 bicyclo[4.2.0]octa-1(6),2,4-triene-3-carbaldehyde 
• 195730-31-5 4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid 
• 138540-82-6 1-phenyl-2-(4-benzocyclobutyl)ethene 
• 138519-05-8 1-(4-methylphenyl)-2-(4-benzocyclobutyl)ethene 
• 55716-66-0 bicyclo[4.2.0]octa-1,3,5-trien-4-amine 

Relevant articles and documents

Novel cross-linking monomer based on benzocyclobutene for an application in microelectronics

A new cross-linking monomer, allyl-bis(benzocyclobuten-4-yl)methylsilane (ABCBMS), was synthesized and its physical properties were investigated. Copolymers of ABCBMS with triethylene glycol dimethacrylate (TGM-3) and bis(methacryloylethylene glycol) carbonate (BMCC-2) were obtained by photo- and thermal polymerization. The final cross-linking of the copolymers took place at 200 °C. Homo- and copolymers of ABCBMS, ABCBMS-TGM-3 (50: 50) and ABCBMS—BMCC-2 (50: 50) exhibit high thermal stability (Td5% = 460, 359, and 352 °C, respectively) and good dielectric properties (ε = 2.7–2.8 and tg δ = (3.7–6.7)?10?4 at 10 GHz).

Rodlike Tetracene Derivatives

Efficient and versatile synthetic access to rodlike tetracene derivatives was developed by means of Diels–Alder cycloaddition, halogenation, halogen–metal exchange, and transition metal mediated coupling reactions. Herein, the synthesis and structural, electrical, and charge-transport properties of three of the resulting materials, namely, 2-(tetracen-2-yl)tetracene, 1,4-bis(2-tetracenyl)benzene, and 2,5-bis(2-tetracenyl)thiophene, are presented. Good crystallization behavior on SiO2 substrates, narrowing of the bandgap by 0.2 eV, and a decrease of the ionization potential of more than 0.5 eV compared to tetracene were observed. Charge-carrier field-effect mobilities on the order of 10?1 cm2 V?1 s?1, on/off ratios of 105, and threshold voltages Vth15 V were found in thin-film organic field-effect transistors prepared by standard high-vacuum deposition techniques.

Preparation method of monobrominated aromatic hydrocarbon compound

The invention discloses a preparation method of a monobrominated aromatic hydrocarbon compound, which comprises the following steps: by using an aromatic hydrocarbon compound as a raw material, wateras a solvent and liquid bromine as a bromine source, reacting at room temperature for 4.5 hours, and after the reaction is finished, carrying out aftertreatment on the obtained reaction mixed solutionto obtain the monobrominated target product. According to the method, a high-selectivity bromination method is realized on the aromatic hydrocarbon compound under the action of water, and the monobrominated aromatic hydrocarbon compound is prepared. The method is high in reaction applicability, mild in condition, high in yield, green and environment-friendly.

ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS

Compounds, methods of use, and processes for making inhibitors of complement Factor D are provided comprising Formula I, I" and I'" or a pharmaceutically acceptable salt or composition thereof. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduces the excessive activation of complement.

Molecular tunnel junctions based on π-conjugated oligoacene thiols and dithiols between Ag, Au, and Pt contacts: Effect of surface linking group and metal work function

The tunneling resistance and electronic structure of metal-molecule-metal junctions based on oligoacene (benzene, naphthalene, anthracene, and tetracene) thiol and dithiol molecules were measured and correlated using conducting probe atomic force microscopy (CP-AFM) in conjunction with ultraviolet photoelectron spectroscopy (UPS). Nanoscopic tunnel junctions (～10 nm2) were formed by contacting oligoacene self-assembled monolayers (SAMs) on flat Ag, Au, or Pt substrates with metalized AFM tips (Ag, Au, or Pt). The low bias (0 exp(βs), where R0 is the contact resistance and β is the tunneling attenuation factor. The R0 values for oligoacene dithiols were 2 orders of magnitude less than those of oligoacene thiols. Likewise, the β value was 0.5 per ring (0.2 A-1) for the dithiol series and 1.0 per ring (0.5 A-1) for the monothiol series, demonstrating that β is not simply a characteristic of the molecular backbone but is strongly affected by the number of chemical (metal-S) contacts. R0 decreased strongly as the contact work function (Φ) increased for both monothiol and dithiol junctions, whereas β was independent of Φ within error. This divergent behavior was explained in terms of the metal-S bond dipoles and the electronic structure of the junction; namely, β is independent of contact type because of weak Fermi level pinning (UPS revealed EF - EHOMO varied only weakly with Φ), but R0 varies strongly with contact type because of the strong metal-S bond dipoles that are responsible for the Fermi level pinning. A previously published triple barrier model for molecular junctions was invoked to rationalize these results in which R0 is determined by the contact barriers, which are proportional to the size of the interfacial bond dipoles, and β is determined by the bridge barrier, E F - EHOMO. Current-voltage (I-V) characteristics obtained over a larger voltage range 0-1 V revealed a characteristic transition voltage Vtrans at which the current increased more sharply with voltage. Vtrans values were generally >0.5 V and were well correlated with the bridge barrier EF - EHOMO. Overall, the combination of electronic structure determination by UPS with length- and work function-dependent transport measurements provides a remarkably comprehensive picture of tunneling transport in molecular junctions based on oligoacenes.

BICYCLO-SUBSTITUTED PYRAZOLON AZO DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF

The bicyclo-substituted pyrazolon-azo derivatives of formula (I) or pharmaceutical acceptable salts, hydrates or solvates thereof, methods for their preparation, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as thrombopoietin (TPO) mimetics and their use as agonists of thrombopoietin receptor are disclosed. The definition of substituents in formula (I) are the same as defined in the description.

Oligo-Tetracenes, Production and Use Thereof

Described are oligotetracenes of formula I which may either be unsubstituted or carry one or more substituents R and R′ which are selected from the group comprising halogen,CN,alkyl or alkoxy radicals containing 1 to 18 carbon atoms,aryl radicals containing up to 10 carbon atoms which may also contain one or moreheteroatoms, and/orfluorinated or perfluorinated alkyl or alkoxy radicals containing 1 to 18 carbon atoms, where n is an integer from 1 to 20, preferably 1 to 6, very particularly preferably 1 or 2, and X stands for a single bond, an alklyene group containing 1 to 6 carbon atoms, a hydrocarbon chain having one or more conjugated double bonds, an aryl group, or a system composed of one or more condensed aromatic rings. In the oligotetracenes according to the invention, one or more of the condensed aromatic six-atom rings may be substituted by a five-atom ring which may also contain a heteroatom. Also described is a method for preparing the referenced oligotetracenes, and use thereof as semiconductors in organic field-effect transistors (OFET's), organic light-emitting diodes (OLED's), sensors, and organic solar cells.

Process for preparing vinylically-unsaturated compounds (II)

A process for preparing a vinylically-unsaturated product compound comprises reacting a halogenated organic compound with a hydrolytically-stable, vinylically-unsaturated precursor compound in the presence of (a) a homogeneous zerovalent palladium catalyst complex, (b) an inorganic hydrogen halide acceptor and (c) diluent, wherein the diluent is water or an aqueous solution containing up to 95% by volume of an organic solvent. The halogenated organic compound is selected from aryl halides, benzyl halides or vinylic halides. The hydrolytically-stable, vinylically-unsaturated precursor compound is selected from hydrocarbon compounds or compounds containing at least one of an oxygen atom, a nitrogen atom, a sulfur atom, a phosphorus atom, silicon atom or a combination thereof.