1073152-35-8Relevant academic research and scientific papers
Highly enantioselective alkynylation of aldehydes catalyzed by a new oxazolidine-titanium complex
Xu, Zhou,Mao, Jincheng,Zhang, Yawen
, p. 1288 - 1292 (2008)
The readily available and inexpensive new chiral oxazolidine 2a in combination with Ti(OiPr)4 was found to catalyze the reaction of an alkynylzinc reagent with various types of aldehydes to generate chiral propargylic alcohols with high enantioselectivities (up to 95%) and excellent yields (up to 98%). The Royal Society of Chemistry.
