1073176-55-2Relevant academic research and scientific papers
A nonpeptidic reverse turn that promotes parallel sheet structure stabilized by C-H...O hydrogen bonds in a cyclopropane γ-peptide
Jones, Christopher R.,Qureshi, M. Khurram N.,Truscott, Fiona R.,Hsu, Shang-Te Danny,Morrison, Angus J.,Smith, Martin D.
supporting information; experimental part, p. 7099 - 7102 (2009/04/12)
(Chemical Equation Presented) A twist of fate: Parallel-turn linkers comprising an amino acid derived alcohol conjoined with an aromatic amide through a flexible linkage adopt reverseturn conformations. Cyclopropane tetra-and hexapeptide analogues form a C-H...O hydrogen-bond-stabilized parallel-sheet conformation (see scheme). NMR studies confirm the presence of hydrogen bonds in these structures.
