107326-19-2Relevant academic research and scientific papers
Sequential ring expansion and ketene elimination reactions in the novel rhodium(I)-catalyzed carbonylation of thiazolidines
Khumtaveeporn, Kanjai,Alper, Howard
, p. 5662 - 5666 (2007/10/02)
1,3-Thiazolidines react with carbon monoxide, in the presence of catalytic quantities of chloro(1,5-cyclooctadiene)rhodium(I) dimer and potassium iodide, to give thiazolidinones in 56-88% yields. Reaction in the absence of KI afforded the six-membered ring thiazin-3-one. The rhodium(I) complex can catalyze the quantitative conversion of the thiazin-3-one to the thiazolidinone under carbon monoxide, with ketene as the reaction by-product. The conversion of thiazolidines to thiazolidinones involves a novel regiospecific insertion of carbon monoxide into one of two ring carbon-nitrogen bonds, as well as a metal-catalyzed ketene elimination process.
On the Selectivity of the Cleavage of 2-Substituted Aziridines in the Synthesis of Thiazolidines
Barbry, Didier,Couturier, Daniel
, p. 1073 - 1074 (2007/10/02)
2-Alkylaziridines react with carbonyl compounds in the presence of hydrogen sulfide to give regioselectively 4-alkylthiazolidines 1.With 2-phenylaziridine 4-phenyl- (1d) and 5-phenylthiazolidine (2d) are obtained, the latter in larger amounts.This result
