1073339-11-3

Basic information

• Product Name: 4,4,5,5-tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane
• Synonyms: 4,4,5,5-tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane
• CAS NO: 1073339-11-3
• Molecular Weight: 276.039
• Mol File: 1073339-11-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4,4,5,5-tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,5,5-tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane(1073339-11-3)
• EPA Substance Registry System: 4,4,5,5-tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane(1073339-11-3)

Safety Data

• Hazardous Substances Data: 1073339-11-3(Hazardous Substances Data)

Upstream product

• 363-72-4 Pentafluorobenzene 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 327-54-8 1,2,4,5-Tetrafluorobenzene 
• 73183-34-3 bis(pinacol)diborane 
• 1835-61-6 1-chloro-2,3,5,6-tetrafluorobenzene 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 511295-01-5 2,3,5,6-tetrafluorophenyl(dihydroxy)borane 
• 1111096-19-5 2-(2,6-difluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 325143-04-2 4,4,5,5-tetramethyl-2-(2,4,6-trifluorophenyl)-1,3,2-dioxaborolane 
• 832114-00-8 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole 
• 863868-37-5 2-(2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 834-89-9 2,3,5,6-tetrafluorobiphenyl 
• 2712-33-6 1,4-di-phenyl-2,3,5,6-tetrafluorobenzene 
• 3883-86-1 2,2',3,3',5,5',6,6'-octafluoro-1,1'-biphenyl 
• 18970-54-2 1,2,4,5-tetrafluoro-3-(phenylethynyl)benzene 
• 327-54-8 1,2,4,5-Tetrafluorobenzene 

Relevant articles and documents

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Protodeboronation of (Hetero)Arylboronic Esters: Direct versus Prehydrolytic Pathways and Self-/Auto-Catalysis

The kinetics and mechanism of the base-catalyzed hydrolysis (ArB(OR)2→ ArB(OH)2) and protodeboronation (ArB(OR)2→ ArH) of a series of boronic esters, encompassing eight different polyols and 10 polyfluoroaryl and heteroaryl moieties, have been investigated by in situ and stopped-flow NMR spectroscopy (19F,1H, and11B), pH-rate dependence, isotope entrainment,2H KIEs, and KS-DFT computations. The study reveals the phenomenological stability of boronic esters under basic aqueous-organic conditions to be highly nuanced. In contrast to common assumption, esterification does not necessarily impart greater stability compared to the corresponding boronic acid. Moreover, hydrolysis of the ester to the boronic acid can be a dominant component of the overall protodeboronation process, augmented by self-, auto-, and oxidative (phenolic) catalysis when the pH is close to the pKaof the boronic acid/ester.

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