1073486-95-9Relevant academic research and scientific papers
Synthesis of highly substituted isoquinolone derivatives by nickel-catalyzed annulation of 2-halobenzamides with alkynes
Liu, Chuan-Che,Parthasarathy, Kanniyappan,Cheng, Chien-Hong
supporting information; experimental part, p. 3518 - 3521 (2010/10/02)
(Equation Presented). An efficient method for the synthesis of substituted 1(2H)-isoquinolone derivatives via nickel-catalyzed annulation of substituted 2-halobenzamides with alkynes is described. This protocol is successfully applied to the total synthes
Palladium-catalyzed carbonylation-decarboxylation of diethyl(2-iodoaryl) malonates with imidoyl chlorides: An efficient route to substituted isoquinolin-1(2H)-ones
Zheng, Zhaoyan,Alper, Howard
supporting information; experimental part, p. 4903 - 4906 (2009/05/07)
(Chemical Equation Presented) A wide variety of substituted isoquinolin-1(2H)-ones were synthesized in reasonable to good yields by the palladium-catalyzed cyclization of diethyl(2-iodoaryl)malonates with imidoyl chlorides and carbon monoxide in tetrahydrofuran. A palladium-catalyzed carbonylation-decarboxylation process may be involved in the one-step synthesis of the isoquinolin-1(2H)-ones.
