1073524-86-3

Basic information

• Product Name: 4,4'-bis[N,N'-di(tert-butoxycarbonyl)isoureido]diphenyl thioether
• Synonyms: 4,4'-bis[N,N'-di(tert-butoxycarbonyl)isoureido]diphenyl thioether
• CAS NO: 1073524-86-3
• Molecular Weight: 702.826
• Mol File: 1073524-86-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,4'-bis[N,N'-di(tert-butoxycarbonyl)isoureido]diphenyl thioether(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-bis[N,N'-di(tert-butoxycarbonyl)isoureido]diphenyl thioether(1073524-86-3)
• EPA Substance Registry System: 4,4'-bis[N,N'-di(tert-butoxycarbonyl)isoureido]diphenyl thioether(1073524-86-3)

Safety Data

• Hazardous Substances Data: 1073524-86-3(Hazardous Substances Data)

Upstream product

• 2664-63-3 4,4'-Thiodiphenol 
• 145013-05-4 tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanethioyl)carbamate 

Relevant articles and documents

Novel synthesis and pharmacological evaluation as α2-adrenoceptor ligands of O-phenylisouronium salts

The synthesis of nine new mono- and bis-O-phenylisouronium compounds (2, 6b-10b and 12b-14b) and their Boc-protected isourea precursors (2a, 6a-10a and 12a-14a) is described. The carbodiimide 4, which was formed, had been suggested as the reactive intermediate species and driving force of the reaction. All final substrates were tested as potential α2-ARs ligands in human brain tissue by means of radioligand binding experiments and were compared to the potential antidepressant 1, as well as other related guanidine containing derivatives.