1073557-86-4Relevant articles and documents
Synthesis of 1,3,4-thiadiazole derivatives as aminopeptidase N inhibitors
Li, Shao-Hua,Li, Gang,Huang, Hui-Ming,Xiong, Fang,Mai, Xi,Kuang, Bin-Hai,Liu, Cheng-Mei,Tu, Guo-Gang
experimental part, p. 67 - 70 (2010/03/04)
Aminopeptidase N (APN) is a zinc-dependent ectopeptidase which plays an important role in the invasion of metastatic tumors. In this study, we report the synthesis and in vitro enzyme inhibition assay of 1,3,4-thiadiazole scaffold compounds. These new com