1074-54-0

Basic information

• Product Name: alpha-methylpiperazine-1-ethanol
• Synonyms: alpha-methylpiperazine-1-ethanol;α-Methyl-1-piperazineethanol;Einecs 214-042-4;1-(1-Piperazinyl)-2-propanol;1-Piperazin-1-yl-propan-2-ol;1-Piperazineethanol, a-methyl-
• CAS NO: 1074-54-0
• Molecular Formula: C₇H₁₆N₂O
• Molecular Weight: 144.21474
• EINECS: 214-042-4
• Mol File: 1074-54-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 252.3 °C at 760 mmHg
• Flash Point: 106.4 °C
• Appearance: /
• Density: 1.007 g/cm³
• Vapor Pressure: 0.00295mmHg at 25°C
• Refractive Index: 1.472
• CAS DataBase Reference: alpha-methylpiperazine-1-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-methylpiperazine-1-ethanol(1074-54-0)
• EPA Substance Registry System: alpha-methylpiperazine-1-ethanol(1074-54-0)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• WGK Germany: 3
• Hazardous Substances Data: 1074-54-0(Hazardous Substances Data)

Usage

General Description

Alpha-methylpiperazine-1-ethanol is a chemical compound that contains a piperazine ring with a methyl group and an ethanol group attached. It is commonly used as a precursor in the synthesis of pharmaceutical drugs and other organic compounds. This chemical has various industrial applications, including as a solvent, corrosion inhibitor, and intermediate in the manufacture of pesticides and surfactants. It is also utilized in the production of polymers and as a stabilizer in photography and color film processing. Additionally, alpha-methylpiperazine-1-ethanol has been investigated for its potential use as a therapeutic agent in the treatment of certain medical conditions.

InChI:InChI=1/C7H16N2O/c1-7(10)6-9-4-2-8-3-5-9/h7-8,10H,2-6H2,1H3

Upstream product

• 13173-24-5 N,N'-bis-allylpiperazine 
• 110-85-0 piperazine 
• 75-56-9 methyloxirane 
• 100500-89-8 2-hydroxy-1-(piperazin-1-yl)propan-1-one 

Downstream Products

• 1193-66-4 2-methyl-1,4-diazabicyclo [2,2,2]octane 
• 77777-03-8 8-Benzylthio-2-[N-(2-hydroxy-propyl)-piperazino]-4-morpholino-pyrimido-[5,4-d]-pyrimidine 
• 90671-94-6 1-{4-[(4-Isopropyl-phenyl)-(4-methyl-isothiazol-5-yl)-methyl]-piperazin-1-yl}-propan-2-ol 
• 110-85-0 piperazine 
• 156339-51-4 2-<4-(2-tert-butoxycarbonylethyl)-1-piperazinyl>-1-methylethyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetate 

Relevant articles and documents

Producing polyurethanes using hydroxy-alkyl piperazine catalyst compositions

Disclosed is a catalytic composition comprising a substance having the general formula: STR1 where R1 is an alkyl group having 1 to 3 C atoms and R2 is a group selected from --H, --CH3 and CH2 CH3. The catalytic composition is odorless and excellent in the urethane forming reaction in production of polyurethane.

HYDROBORATION OF 1,4-DIALLYLPIPERAZINE

Hydroboration of 1,4-diallylpiperazine (I) with triethylamine-borane afforded 5,8-diaza-1,9-diboradispirotetradecane (II). 1,4-Diallylpiperazine dihydrochloride reacted with sodium borohydride to give 1,4-diallylpiperazine-diborane (V).Ethanolysis of II furnished 1,4-bis(3-diethoxyborylpropyl)piperazine (IV).The products of hydroboration of I were subjected to hydrolysis with hydrochloric acid and subsequent oxidation with alkaline hydrogen peroxide and the obtained mixtures were analyzed by gas-liquid chromatography and mass spectrometry.