1074-87-9

Usage

Synthesis Reference(s)

Synthetic Communications, 36, p. 1051, 2006 DOI: 10.1080/00397910500503470

InChI:InChI=1/C9H9NO/c11-6-8-3-1-2-7-4-5-10-9(7)8/h1-5,10-11H,6H2

Upstream product

• 5471-82-9 methyl 3-methyl-2-nitrobenzoate 
• 80866-76-8 2-methyl-6-hydroxymethyl-1-nitrobenzene 
• 886841-16-3 2-nitro-3-pivaloylmethyltoluene 
• 1026131-79-2 2,2-Dimethyl-propionic acid 2-nitro-3-((E)-2-pyrrolidin-1-yl-vinyl)-benzyl ester 
• 886841-17-4 7-tetrahydropyran-2-yloxymethyl-indole 
• 93247-78-0 methyl 1H-indole-7-carboxylate 
• 25128-35-2 isatin-7-carboxylic acid 
• 522638-27-3 2-nitro-3-tetrahydropyran-2-yloxymethyltoluene 
• 18710-86-6 2-(3-methyl-2-nitrophenyl)acetic acid 

Downstream Products

• 1074-88-0 1H-indole-7-carbaldehyde 
• 886993-17-5 C₃₄H₅₀N₂O₃SSi 
• 886990-82-5 C₃₄H₅₀N₂O₃SSi 
• 886990-83-6 C₃₉H₅₈N₂O₅SSi 
• 104682-97-5 methyl 3-(indol-7-yl)acrylate 
• 1034895-78-7 7-methoxymethyl-1-methyl-1H-indole 
• 1034895-68-5 7-(tert-butyldiphenyl-silanyloxymethyl)-1H-indole 
• 854778-61-3 (1-methyl-1H-indol-7-yl)-methanol 

Relevant academic research and scientific papers

Sulfonamide peri-substituted bicyclics for occlusive artery disease

Acyl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:

CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.

Simple synthesis of 7-formyl-indole

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Certain indole derivatives useful as leukotriene antagonists

A compound of the formula STR1 in which R1 is hydrogen, halo, C1-4 alkyl, C1-4 alkoxy, nitrile, optionally protected carboxy, optionally protected tetrazolyl, trihalomethyl, hydroxy-C1-4 alkyl, aldehydo, --CH2 Z, --CH=CH--Z or --CH2 CH2 Z where Z is optionally protected carboxy or optionally protected tetrazolyl; R2 is halo, nitrile, an optionally protected acid group or --CONR7 R8 where R7 and R8 are each hydrogen or C1-4 alkyl; R3 and R4 are each hydrogen, C1-4 alkyl, optionally substituted phenyl, or C1-4 alkyl substituted by --CONR7 R8 or an optionally protected acid group; R5 is STR2 where W is --CH=CH--, --CH=N--, --N=CH--, --O-- or --S--, R9 is hydrogen, halo, C1-4 alkyl, C1-4 alkoxy or trihalomethyl, and R10 is hydrogen, C1-4 alkyl, C2-6 alkenyl, C3-6 cycloalkyl or C1-4 alkyl-C3-6 cycloalkyl; R6 is hydrogen or C1-4 alkyl; X is --O--(CH2)n CR11 R12, --CR11 R12 --, --CR11 R12.(CH2)n.CR13 R14 -- or --CR11 =CR12 -- where R11, R12, R13 and R14 are each hydrogen or C1-4 alkyl, and n is 0, 1 or 2; and Y is --O--CR15 R16 --, --CR15 =CR16 -- or --CR15 R16.CR17 R18 -- where R15, R16, R17 and R18 are each hydrogen or C 1-4 alkyl; or a salt thereof. The compounds in unprotected form are active as leukotriene antagonists.

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